The American Journal of Medicine
Volume 123, Issue 9 , Pages 777-784, September 2010

Practical Considerations for Planning a Therapeutic Apheresis Procedure

  • Suresh G. Shelat, MD, PhD

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Suresh G. Shelat, MD, PhD, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104

Department of Pathology, and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia

published online 11 June 2010.

Abstract 

The general medicine and critical care services often care for patients that require therapeutic apheresis. Apheresis procedures are performed for various hematologic, neurological, renal, autoimmune, metabolic, and other indications. To facilitate a prompt start to the procedure, the clinical team must coordinate efforts with several services, including those that perform the apheresis procedure, establish venous access, and provide blood or replacement products, in addition to the pharmacy and clinical laboratory. Some of these tasks are performed typically by the clinical teams, while others are performed typically by the apheresis team. Presented and discussed are the indications for therapeutic apheresis, calculations for the ordering of blood products, and several important and practical details to consider, thus preventing delays in starting the apheresis procedure.

Keywords: Erythrocytapheresis, Leukapheresis, Plasmapheresis, Thrombocytapheresis

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 Funding: None.

 Conflict of Interest: There are no conflicts of interest to report.

 Authorship: The author accepts sole responsibility for the data and for manuscript preparation.

PII: S0002-9343(10)00231-7

doi:10.1016/j.amjmed.2010.01.022

The American Journal of Medicine
Volume 123, Issue 9 , Pages 777-784, September 2010