The American Journal of Medicine
Volume 123, Issue 5 , Pages 409-413, May 2010

Addison Disease in Adults: Diagnosis and Management

  • Ali J. Chakera, MBChB, MRCP
  • ,
  • Bijay Vaidya, PhD, FRCP

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Bijay Vaidya, PhD, Department of Endocrinology, Royal Devon & Exeter Hospital, Exeter EX2 5DW, UK

Department of Endocrinology, Royal Devon & Exeter Hospital, Exeter, UK

Abstract 

Addison disease is a rare but potentially fatal disorder of the adrenal glands. Its manifestations are often confused with many common disorders, and a high index of suspicion is required for the diagnosis. Optimum steroid replacement and patient education are vital for good quality of life and to prevent acute adrenal crisis in this condition.

Keywords: Addison disease, Adrenal, Glucocorticoid, Hypoadrenalism, Mineralocorticoid

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 Funding: The work of Dr. Vaidya was partly supported by the Peninsula Collaboration for Leadership in Applied Health Research and Care (PenCLAHRC) Funding.

 Conflict of Interest: None.

 Authorship: Both authors had access to the data and a role in writing the manuscript.

PII: S0002-9343(10)00065-3

doi:10.1016/j.amjmed.2009.12.017

The American Journal of Medicine
Volume 123, Issue 5 , Pages 409-413, May 2010