The American Journal of Medicine
Volume 123, Issue 3 , Pages 223-224 , March 2010

A Post-cure Complication

  • Joana Nunes, MD

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Joana Nunes, MD, Hospital Santa Maria, Avenida Professor Egas Moniz, 1649-035, Lisboa, Portugal
    • ,
  • Rui Tato Marinho, MD, PhD
    • ,
  • José Velosa, MD, PhD

References 

  1. Ghany MG, Strader DB, Thomas DL, Seeff LB American Association for the Study of Liver Diseases. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology. 2009;49:1335–1374
  2. Gallelli L, Guadagnino V, Caroleo B, et al. Cutaneous ulceration induced by interferon alfa. Ann Pharmacother. 2004;38:173–174
  3. Dalmau J, Pimentel CL, Puig L, et al. Cutaneous necrosis after injection of polyethylene glycol-modified interferon alfa. J Am Acad Dermatol. 2005;53:62–66
  4. Protzer U, Ochsendorf FR, Leopolder-Ochsendorf A, Holtermüller KH. Exacerbation of lichen planus during interferon alfa-2a therapy for chronic active hepatitis C. Gastroenterology. 1993;104:903–905
  5. Soares Almeida LM, Requena L, Kutzner H, et al. Localized panniculitis secondary to subcutaneous glatiramer acetate injections for the treatment of multiple sclerosis: a clinicopathologic and immunohistochemical study. J Am Acad Dermatol. 2006;55:968–974
  6. Beiske AG, Myhr KM. Lipoatrophy: a non-reversible complication of subcutaneous interferon beta-1a treatment of multiple sclerosis. J Neurol. 2006;253:377–378
  7. Mancardi GL, Murialdo A, Drago F, et al. Localized lipoatrophy after prolonged treatment with copolymer 1. J Neurol. 2000;247:220–221
  8. Buttmann M, Goebeler M, Toksoy A, et al. Subcutaneous interferon beta injections in patients with multiple sclerosis initiate inflammatory skin reactions by local chemokine induction. J Neuroimmunol. 2005;168:175–192
  9. Cottoni F, Bolognini S, Deplano A. Skin reaction in antiviral therapy for chronic hepatitis C: a role for polyethylene glycol interferon?. Acta Derm Venereol. 2004;84:120–123

 Parwathi “Uma” Paniker, MD, Section Editor

 Conflict of Interest: The authors have no conflict of interest.

 Funding: We had no funding sources.

 Authorship: All authors had access to the data and participated in the preparation of the manuscript.

PII: S0002-9343(09)01080-8

doi: 10.1016/j.amjmed.2009.12.009

The American Journal of Medicine
Volume 123, Issue 3 , Pages 223-224 , March 2010

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