« Previous
Next »
The American Journal of Medicine
Volume 123, Issue 4
, Pages 358-366.e2
, April 2010
Systematic Review of the Symptom Burden, Quality of Life Impairment and Costs Associated with Peptic Ulcer Disease
References
- Prevalence of gastrointestinal diseases in two British national birth cohorts. Gut. 2003;52:1117–1121
- . Genetic markers for peptic ulcer (A study of 3387 men aged 54 to 74 years: the Copenhagen Male Study). Scand J Gastroenterol. 1997;32:16–21
- Acute upper GI bleeding: did anything change? (Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000). Am J Gastroenterol. 2003;98:1494–1499
- . Systematic review of the epidemiology of complicated peptic ulcer: incidence, recurrence, risk factors and mortality. Gastroenterology. 2008;134(4 Suppl 1):A32
- Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ. 2004;329(7456):15–19
- . Prevention and treatment of gastrointestinal symptoms and complications due to NSAIDs. Best Pract Res Clin Gastroenterol. 2001;15:755–773
- . Absence of abdominal pain in elderly patients with peptic ulcer. Age Ageing. 1984;13:120–123
- . Gastrointestinal symptoms in the irritable bowel compared with peptic ulcer and inflammatory bowel disease. Gut. 1984;25:1089–1092
- . Benign gastric ulceration in a health district: incidence and presentation. Postgrad Med J. 1985;61(718):695–700
- . Comparison of the clinical features and illness behaviour of patients presenting with dyspepsia of unknown cause (essential dyspepsia) and organic disease. Aust N Z J Med. 1986;16:352–359
- . Nocturnal pain and duodenal ulcer. Br J Clin Pract. 1988;42:198–199
- . Duodenal ulcer in the elderly. J Clin Gastroenterol. 1989;11:502–506
- The predictive value of history in dyspepsia. Scand J Gastroenterol. 1990;25:689–697
- . Pattern of duodenal ulcer in Karachi. J Pak Med Assoc. 1990;40:212–215
- . Site of duodenal ulcer and its influence on the mode of presentation and prognosis. J Pak Med Assoc. 1990;40:238–239
- Studies of gastric ulcer disease by community-based gastroenterologists. Am J Gastroenterol. 1990;85:824–828
- . Changing pattern of peptic ulcer in India (An endoscopic study of 1,188 ulcer patients). J Clin Gastroenterol. 1991;13:575–579
- Prevalences of endoscopic and histological findings in subjects with and without dyspepsia. BMJ. 1991;302(6779):749–752
- . Diagnostic value of some subjective and objective symptoms of gastric ulcer. Mater Med Pol. 1992;24:82–83
- . Gastric ulcer in Karachi. J Pak Med Assoc. 1992;42:207–210
- The study of discriminant values of dyspeptic symptoms for identifying the etiology of dyspepsia. J Med Assoc Thai. 1992;75:341–349
- Ulcer risk factors: interactions between Helicobacter pylori infection, nonsteroidal use, and age. Am J Med. 1993;94:413–418
- Open access endoscopy: a large-scale analysis of its use in dyspeptic patients. J Clin Gastroenterol. 1993;16:149–153discussion 153-154
- How much ulcer is ulcer-like? Diagnostic determinants of peptic ulcer in open access gastroscopy. Fam Pract. 1994;11:382–388
- . Dyspepsia: preliminary experience with upper gastrointestinal fibreoptic endoscopy in Eldoret. East Afr Med J. 1994;71:261–263
- . Aetiology and dynamics of dyspepsia in Shimla: a study of 500 patients. Trop Gastroenterol. 1994;15:213–218
- . Chronic upper abdominal pain due to duodenal ulcer and other structural and functional causes: its localization and nocturnal occurrence. J Gastroenterol Hepatol. 1996;11:515–519
- . The clinical presentation of peptic ulcer disease. Neth J Med. 1997;50:115–119
- . Duodenal ulcer and Helicobacter pylori infection at high altitude: experience from southern Saudi Arabia. Can J Gastroenterol. 1997;11:313–316
- . Clinical presentation of peptic ulcer in the elderly. Gerontology. 1997;43:283–288
- . Dyspepsia and Helicobacter pylori infection: analysis of 200 Kuwaiti patients referred for endoscopy. Ann Saudi Med. 1998;18:502–505
- . Peptic ulcer in the very old patients. Gerontology. 2000;46:271–275
- Absence of abdominal pain in older persons with endoscopic ulcers: a prospective study. Am J Gastroenterol. 2001;96:380–384
- . Evaluation of symptom presentation in dyspeptic patients referred for upper gastrointestinal endoscopy in Estonia. Croat Med J. 2004;45:592–598
- . A prospective, randomized study on duodenal ulcer. Ann Fundeni Hosp. 2004;9(1-2):10–12
- Prevalence of Helicobacter pylori infection in patients with peptic ulcer diseases. Saudi Med J. 2006;27:621–626
- Well-being and gastrointestinal symptoms among patients referred to endoscopy owing to suspected duodenal ulcer. Scand J Gastroenterol. 1995;30:1046–1052
- . GSRS – a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci. 1988;33:129–134
- Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease. Scand J Gastroenterol Suppl. 1996;221:8–13
- . The comparison of health-related quality of life (HRQL) in patients with GERD, peptic ulcer disease and ulcerative colitis. Adv Med Sci. 2006;51:142–147
- . A ‘quality of life questionnaire’ adapted to duodenal ulcer therapeutic trials. Scand J Gastroenterol Suppl. 1994;29(206):40–43
- Quality of life in patients with upper gastrointestinal symptoms (An improved evaluation of treatment regimens?). Scand J Gastroenterol. 1993;28:681–687
- . Quality of life assessments in patients with peptic ulcer during treatment and follow-up. Scand J Gastroenterol Suppl. 1993;199:34–35
- . Assessment of quality of life among patients with suspected duodenal ulcer. Scand J Gastroenterol Suppl. 1993;199:32–33
- . Quality of life assessments in the evaluation of gastroesophageal reflux and peptic ulcer disease before, during and after treatment. Scand J Gastroenterol Suppl. 1995;208:133–135
- Quality of life in duodenal ulcer treatment: a comparison of omeprazole and ranitidine in acute and intermittent treatment. Psychol Health Med. 1998;3:417–427
- . Quality of life and Helicobacter pylori eradication. Scand J Gastroenterol Suppl. 1996;221:18–20
- . Discriminant analysis of factors distinguishing patients with functional dyspepsia from patients with duodenal ulcer: significance of somatization. Dig Dis Sci. 1995;40:1105–1111
- A quality of life study in five hundred and eighty-one duodenal ulcer patients (Maintenance versus intermittent treatment with nizatidine). Scand J Gastroenterol Suppl. 1994;206:44–51
- Pain and quality of life in patients with acute duodenal ulcer treated with ranitidine. Aliment Pharmacol Ther. 1995;9:433–439
- Measuring change in quality of life in response to Helicobacter pylori eradication in peptic ulcer disease: the QOLRAD. Dig Dis Sci. 2001;46:571–580
- Long-term effect of Helicobacter pylori eradication on quality of life, body mass index, and newly developed diseases in Japanese patients with peptic ulcer disease. Hepatogastroenterology. 2002;49(47):1298–1302
- Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding. Health Technol Assess. 2007;11(51):1–164
- Quality of life measurement clarifies the cost-effectiveness of Helicobacter pylori eradication in peptic ulcer disease and uninvestigated dyspepsia. Am J Gastroenterol. 2001;96:338–347
- . Absenteeism of shift and day workers with special reference to peptic ulcer. Asia Pac J Public Health. 1988;2:112–119
- . Long-term technology assessment (Mortality, hospitalization, and work loss due to peptic ulcer and gastritis/duodenitis in the Federal Republic of Germany). Int J Technol Assess Health Care. 1989;5:215–226
- . Changes in peptic ulcer and gastritis/duodenitis in Great Britain, 1970-1985. J Clin Gastroenterol. 1990;12:100–108
- The economic impact of GERD and PUD: examination of direct and indirect costs using a large integrated employer claims database database. Curr Med Res Opin. 2005;21:535–544
- . Health impact of peptic ulcer in the United States. Am J Gastroenterol. 1997;92:614–620
- . Work loss costs due to peptic ulcer disease and gastroesophageal reflux disease in a health maintenance organization. Am J Gastroenterol. 2000;95:788–792
- . Pharmaco-economic considerations in the long-term management of peptic ulcer disease. Aliment Pharmacol Ther Suppl. 1993;7:41–48
- . World Development Indicators 2008. http://web.worldbank.org/WBSITE/EXTERNAL/DATASTATISTICS/0,,contentMDK:22151356∾pagePK:64133150∾piPK:64133175∾theSitePK:239419,00.html
- . Historical National Population Estimates: July 1, 1900-July 1 1995. Washington DC: Government Printing Office; 2000;
- The burden of selected digestive diseases in the United States. Gastroenterology. 2002;122:1500–1511
- . Economic burden of NSAID-induced gastropathy in Sweden. Scand J Gastroenterol. 2001;36:775–779
- . Demographic Analysis (Demography). Stockholm: Statistics Sweden; 2008;
- . The description of outcomes in Medicare patients hospitalized with peptic ulcer disease. Am J Gastroenterol. 2000;95:264–270
- Costs of acid-related disorders to a health maintenance organization. Am J Med. 1997;103:520–528
- . Prediction of resource utilization and case cost for acute nonvariceal upper gastrointestinal hemorrhage at a Canadian community hospital. Am J Gastroenterol. 1999;94:1841–1846
- . Demographic predictors of resource utilization for bleeding peptic ulcer disease: the Ontario GI Bleed Study. J Clin Gastroenterol. 1999;29:165–170
- Prevalence and cost of hospitalization for gastrointestinal complications related to peptic ulcers with bleeding or perforation: comparison of two national databases. Am J Manag Care. 1998;4:399–409
- . The cost of gastro-oesophageal reflux disease, dyspepsia and peptic ulcer disease in Sweden. Pharmacoeconomics. 2002;20:347–355
- Costs of treating bleeding and perforated peptic ulcers in the Netherlands. J Rheumatol. 2004;31:788–791
- Impacting cost and appropriateness of stress ulcer prophylaxis at a university medical center. Crit Care Med. 1997;25:1678–1684
- . Work loss costs due to peptic ulcer disease and gastroesophageal reflux disease in a health maintenance organization. Am J Gastroenterol. 2000;95:788–792
- . Economic burden of NSAID-induced gastropathy in Sweden. Scand J Gastroenterol. 2001;36:775–779
- Early reintroduction of aspirin with proton pump inhibitor after endoscopic hemostasis for peptic ulcer bleeding: final results of a double blinded randomized study. Gut. 2007;56(Suppl 3):A27
- ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. Am J Gastroenterol. 2008;103:2890–2907
- . Underutilization of gastroprotective strategies in aspirin users at increased risk of upper gastrointestinal complications. Aliment Pharmacol Ther. 2008;28:88–96
Funding: Writing support was provided by Dr. Catherine Henderson (Research Evaluation Unit, Oxford PharmaGenesis Ltd, Oxford, UK), funded by AstraZeneca R&D Mölndal, Sweden.
Conflict of Interest: Dr. Alan Barkun is a consultant for AstraZeneca Inc. Dr. Grigorios Leontiadis has received speaker honoraria from AstraZeneca, Sanofi-Aventis, GlaxoSmithKline, and Janssen-Cilag.
Authorship: This work is original, and the authors meet the criteria for authorship and accept responsibility for the scientific content of the manuscript.
PII: S0002-9343(09)01068-7
doi: 10.1016/j.amjmed.2009.09.031
© 2010 Elsevier Inc. All rights reserved.
« Previous
Next »
The American Journal of Medicine
Volume 123, Issue 4
, Pages 358-366.e2
, April 2010

