The American Journal of Medicine
Volume 123, Issue 7 , Pages 596-597 , July 2010

Liver Palms (Palmar Erythema)

  • Amit Nautiyal, MD

      Affiliations

    • Department of Medicine, University of Wisconsin, Madison, Wis
    • Corresponding Author InformationRequests for reprints should be addressed to Amit Nautiyal, MD, Department of Medicine, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792
    • ,
  • Kapil B. Chopra, MD, AGAF

      Affiliations

    • Department of Medicine, Division of Gastroenterology, Hepatology & Nutrition, University of Pittsburgh, Pa

References 

  1. Niederau C, Lange S, Fruhauf M, Thiel A. Cutaneous signs of liver disease: value for prognosis of severe fibrosis and cirrhosis. Liver Int. 2008;28:659–666Epub 2008 Feb 26
  2. Perera GA. A note on palmar erythema (so-called liver palms). JAMA. 1942;119:1417–1418
  3. Bean W. Acquired palmar erythema and cutaneous vascular ‘spiders’. Am Heart J. 1943;25:463–477
  4. Walsh EN, Becker SW. Erythema palmare and naevus-araneus-like telangiectases. Arch Derm Syphilol. 1941;44:616–630
  5. Maruyama Y, Adachi Y, Aoki N, et al. Mechanism of feminization in male patients with non-alcoholic liver cirrhosis: role of sex hormone-binding globulin. Gastroenterol Jpn. 1991;26:435–439
  6. Fitzpatrick T, Arndt K, Clark W, et al. Dermatology in General Medicine. New York: McGraw-Hill; 1971;
  7. Crawford D, Powell L, Halliday J. Factor's influencing disease expression in hemochromatosis. Ann Rev Nutr. 1996;16:139–160
  8. Massarrat S, Fallahazad V, Kamalian N. Clinical, biochemical and imaging-verified regression of hepatitis B-induced cirrhosis. Liver Int. 2004;24:105–109
  9. Cribier B, Samain F, Vetter D, et al. Systematic cutaneous examination in hepatitis C virus infected patients. Acta Derm Venereol. 1998;78:355–357
  10. Clayton PT. Diagnosis of inherited disorders of liver metabolism. J Inherit Metab Dis. 2003;26(2-3):135–146
  11. Bean WB. A note on the development of cutaneous arterial ‘spiders’ and palmar erythema in persons with liver disease and their development following the administration of estrogens. Am J Med Sci. 1942;204:251–252
  12. Chopra IJ, Abraham GE, Chopra U, et al. Alterations in circulating estradiol-17 in male patients with Graves' disease. N Engl J Med. 1972;286:124–129
  13. Bland JH, O'Brien R, Bouchard RE. Palmar erythema and spider angiomata in rheumatoid arthritis. Ann Intern Med. 1958;48:1026–1031
  14. Noble JP, Boisnic S, Branchet-Gumila MC, Poisson M. Palmar erythema: cutaneous marker of neoplasms. Dermatology. 2002;204:209–213
  15. Serrao R, Zirwas M, English JC. Palmar erythema. Am J Clin Dermatol. 2007;8:347–356

 Thomas J. Marrie, MD, Section Editor

 Funding: None.

 Conflict of Interest: None.

 Authorship: We verify that both authors had access to the data and a role in writing the manuscript.

PII: S0002-9343(09)01015-8

doi: 10.1016/j.amjmed.2009.09.025

The American Journal of Medicine
Volume 123, Issue 7 , Pages 596-597 , July 2010

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