The American Journal of Medicine
Volume 123, Issue 2 , Pages 166-172 , February 2010

Contemporary Trends in Evidence-based Treatment for Acute Myocardial Infarction

  • Marco Fornasini, MD, PhD

      Affiliations

    • College of Health Sciences, Universidad San Francisco de Quito, Quito, Ecuador
    • ,
  • Jorge Yarzebski, MD, MPH

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • ,
  • David Chiriboga, MD, MPH

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • ,
  • Darleen Lessard, MS

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • ,
  • Frederick A. Spencer, MD

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • Department of Medicine, McMaster University, Hamilton, Ontario
    • ,
  • Philip Aurigemma, BS

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • ,
  • Joel M. Gore, MD

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • ,
  • Robert J. Goldberg, PhD

      Affiliations

    • Department of Medicine, University of Massachusetts Medical School, Worcester
    • Corresponding Author InformationRequests for reprints should be addressed to Robert J. Goldberg, PhD, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655

References 

  1. American Heart Association. Heart Disease and Stroke Statistics–2007 Update. Dallas, TX: American Heart Association; 2007;
  2. Yusuf S, Sleight P, Held P, McMahon S. Routine medical management of acute myocardial infarction: lessons from overviews of recent randomized controlled trials. Circulation. 1990;82(Suppl II):II117–II134
  3. Gunnar RM, Passamani ER, Bourdillon PD, et al. Guidelines for the early management of patients with acute myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (Subcommittee to Develop Guidelines for the Early Management of Patients With Acute myocardial infarction). J Am Coll Cardiol. 1990;16:249–292
  4. Ryan TJ, Anderson JL, Antman EM, et al. ACC/AHA guidelines for the management of patients with acute myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute myocardial infarction). J Am Coll Cardiol. 1996;28:1328–1428
  5. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina). Circulation. 2002;106:1893–1900
  6. Antman EM, Anbe DT, Armstrong PW, et al. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of patients with acute myocardial infarction). J Am Coll Cardiol. 2004;44:E1–E211
  7. Maynard C, Litwin PE, Martin JS, Weaver WD. Gender differences in the treatment and outcome of acute myocardial infarction: results from the Myocardial Infarction Triage and Intervention Registry. Arch Intern Med. 1992;152:972–976
  8. Spencer FA, Lessard D, Yarzebski J, et al. Decade-long changes in the use of combination evidence-based medical therapy at discharge for patients surviving acute myocardial infarction. Am Heart J. 2005;150:838–844
  9. McLaughlin TJ, Soumerai SB, Willison DJ, et al. Adherence to national guidelines for drug treatment of suspected acute myocardial infarction: evidence for undertreatment in women and the elderly. Arch Intern Med. 1996;156:799–805
  10. Goldberg RJ, Gore JM, Alpert JS, Dalen JE. Recent changes in attack and survival rates of acute myocardial infarction (1975 through 1981) (The Worcester Heart Attack Study). JAMA. 1986;255:2774–2779
  11. Goldberg RJ, Yarzebski J, Lessard D, Gore JM. A two-decades (1975 to 1995) long experience in the incidence, in-hospital and long-term case-fatality rates of acute myocardial infarction: a community-wide perspective. J Am Coll Cardiol. 1999;33:1533–1539
  12. Floyd KC, Yarzebski J, Spencer FA, et al. A 30 year perspective (1975-2005) into the changing landscape of patients hospitalized with initial acute myocardial infarction: Worcester Heart Attack Study. Circ Cardiovasc Qual Outcomes. 2009;2:88–95
  13. Goldberg RJ, Spencer FA, Steg PG, et al. Global Registry of Acute Coronary Events Investigators Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century. Arch Intern Med. 2007;167:1766–1773
  14. Vaccarino V, Krumholz HM, Berkman LF, Horwitz RI. Sex differences in mortality after myocardial infarction. Circulation. 1995;91:1861–1871
  15. Spencer FA, Frederick PD, Goldberg RJ, et al. National Registry of Myocardial Infarction-4 Investigators Use of combination evidence-based medical therapy prior to acute myocardial infarction (from the National Registry of Myocardial Infarction-4). Am J Cardiol. 2005;96:922–926
  16. Vaccarino V, Horwitz RI, Meehan TP, et al. Sex differences in mortality after acute myocardial infarction: evidence for a sex-age interaction. Arch Intern Med. 1998;158:2054–2062
  17. Harrold LR, Lessard D, Yarzebski J, et al. Age and sex differences in the treatment of patients with initial acute myocardial infarction: a community-wide perspective. Cardiology. 2003;99:39–46
  18. Wald NJ, Law MR. A strategy to reduce cardiovascular disease by more than 80%. Br Med J. 2003;326:1419–1424
  19. Spencer FA, Scleparis G, Goldberg RJ, et al. Decade long trends (1986 to 1997) in the medical management of patients with acute myocardial infarction: a community-wide perspective. Am Heart J. 2001;142:594–603
  20. Spencer FA, Goldberg RJ, Frederick PD, et al. Age and the utilization of cardiac catheterization following uncomplicated first acute myocardial infarction treated with thrombolytic therapy (The Second National Registry of Myocardial Infarction [NRMI-2]). Am J Cardiol. 2001;88:107–111
  21. Stafford RS, Radley DC. The underutilization of cardiac medications of proven benefit, 1990 to 2002. J Am Coll Cardiol. 2003;41:56–61
  22. Mehta RH, Montoye CK, Gallogly M, et al. Improving quality of care for acute myocardial infarction: the guidelines applied in practice (GAP) initiative. JAMA. 2002;287:1269–1276
  23. Lewis WR, Peterson ED, Cannon CP, et al. An organized approach to the improvement in guideline adherence for acute myocardial infarction (Results with the Get With The Guidelines Quality Improvement Program). Arch Intern Med. 2008;168:1813–1819
  24. Mehta RH, Roe MT, Chen AY, et al. Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative. Arch Intern Med. 2006;166:2027–2034

 Funding: National Institutes of Health (RO1 HL35434).

 Conflict of Interest: None of the authors have any conflicts of interest associated with the work presented in this manuscript.

 Authorship: All authors had access to the data and played a role in writing this manuscript.

PII: S0002-9343(09)00872-9

doi: 10.1016/j.amjmed.2009.06.031

The American Journal of Medicine
Volume 123, Issue 2 , Pages 166-172 , February 2010

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