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The American Journal of Medicine
Volume 122, Issue 11
, Pages 1016-1022.e1
, November 2009
Bayesian Meta-analysis of Hormone Therapy and Mortality in Younger Postmenopausal Women
References
- . Prolonged estrogen therapy in postmenopausal women. J Am Med Assoc. 1959;171:1637–1642
- . Increased incidence of coronary heart disease in women castrated prior to the menopause. Arch Intern Med. 1959;104:908–913
- . Specific procedures for the elimination of the menopause. West J Surg Obstet Gynecol. 1963;71:110–121
- Estrogen use and all-cause mortality (Preliminary results from the Lipid Research Clinics Program Follow-Up Study). JAMA. 1983;249:903–906
- . Noncontraceptive estrogens and mortality: long-term follow-up of women in the Walnut Creek Study. Obstet Gynecol. 1987;70(3 Pt 1):289–293
- Estrogen replacement therapy and mortality among older women (The study of osteoporotic fractures). Arch Intern Med. 1997;157:2181–2187
- Postmenopausal hormone therapy and mortality. N Engl J Med. 1997;336:1769–1775
- . Increased longevity in older users of postmenopausal estrogen therapy: the Leisure World Cohort Study. Menopause. 2006;13:12–18
- . Estrogen replacement therapy: an overview. Am J Obstet Gynecol. 1989;161(6 Pt 2):1825–1827
- Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321–333
- Mortality associated with hormone replacement therapy in younger and older women: a meta-analysis. J Gen Intern Med. 2004;19:791–804
- . Review: hormone replacement therapy may reduce the risk for death in younger but not older postmenopausal women. ACP J Club. 2005;142:1
- . Brief report: coronary heart disease events associated with hormone therapy in younger and older women (A meta-analysis). J Gen Intern Med. 2006;21:363–366
- Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA. 2007;297:1465–1477
- . The cost-effectiveness of hormone therapy in younger and older postmenopausal women. Am J Med. 2009;122:42–52
- . Meta-analysis of Controlled Clinical Trials. Chichester, England: John Wiley & Sons; 2002;
- . Bayesian Approaches to Clinical Trials and Health-care Evaluation. Chichester, England: John Wiley & Sons; 2004;
- . Bayesian methods in meta-analysis and evidence synthesis. Stat Methods Med Res. 2001;10:277–303
- Seven items were identified for inclusion when reporting a Bayesian analysis of a clinical study. J Clin Epidemiol. 2005;58:261–268
- . Bayesian random effects meta-analysis of trials with binary outcomes: methods for the absolute risk difference and relative risk scales. Stat Med. 2002;21:1601–1623
- How vague is vague? (A simulation study of the impact of the use of vague prior distributions in MCMC using WinBUGS). Stat Med. 2005;24:2401–2428
- . Borrowing strength from external trials in a meta-analysis. Stat Med. 1996;15(24):2733–2749
- . Being sceptical about meta-analyses: a Bayesian perspective on magnesium trials in myocardial infarction. Int J Epidemiol. 2002;31:96–104
- . Overcoming the limitations of current meta-analysis of randomised controlled trials. Lancet. 1998;351(9095):47–52
- Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study. Circulation. 1987;75:1102–1109
- Postmenopausal estrogen use and mortality (Results from a prospective study in a defined, homogeneous community). Am J Epidemiol. 1988;128:606–614
- Hormonal replacement therapy and morbidity and mortality in a prospective study of postmenopausal women. Am J Public Health. 1995;85(8 Pt 1):1128–1132
- Breast cancer incidence, case-fatality and breast cancer mortality in Danish women using hormone replacement therapy—a prospective observational study. Int J Epidemiol. 2005;34:931–935
- . Hormone replacement therapy and distensibility of carotid arteries in postmenopausal women: a randomized, controlled trial. J Am Coll Cardiol. 2000;36:1789–1796
- . Effects of transdermal estradiol delivered by a matrix patch on bone density in hysterectomized, postmenopausal women: a 2-year placebo-controlled trial. Osteoporos Int. 2002;13:176–183
- . The effect of 17beta-estradiol at doses of 0.5, 1 and 2 mg compared with placebo on early postmenopausal bone loss in hysterectomized women. Osteoporos Int. 2002;13:309–316
- . Estrogen replacement therapy for ovarian carcinoma survivors: a randomized controlled trial. Cancer. 1999;86:1013–1018
- . Effect of hormone replacement therapy on bone mass in rheumatoid arthritis patients treated with and without steroids. Arthritis Rheum. 1994;37:1499–1505
- . Long-term effects of hormone replacement therapy on symptoms of angina pectoris, quality of life and compliance in women with coronary artery disease. Maturitas. 1998;28:235–242
- Prevention of femoral and lumbar bone loss with hormone replacement therapy and vitamin D3 in early postmenopausal women: a population-based 5-year randomized trial. J Clin Endocrinol Metab. 1999;84:546–552
- Influence of estrogen-progestin replacement therapy and exercise on lumbar spine mobility and low back symptoms in a healthy early postmenopausal female population: a 2-year randomized controlled trial. Eur Spine J. 1998;7:381–386
- Long-term prevention of postmenopausal osteoporosis by oestrogen (Evidence for an increased bone mass after delayed onset of oestrogen treatment). Lancet. 1976;1(7968):1038–1041
- Effects of hormone replacement therapy in rheumatoid arthritis: a double blind placebo-controlled study. Ann Rheum Dis. 1994;53:54–57
- Randomized, double-blind, placebo-controlled study of the effects of raloxifene and conjugated equine estrogen on plasma homocysteine levels in healthy postmenopausal women. Fertil Steril. 1998;70:1085–1089
- Hormonal replacement therapy reduces forearm fracture incidence in recent postmenopausal women - results of the Danish Osteoporosis Prevention Study. Maturitas. 2000;36:181–193
- . Estrogen replacement therapy II: a prospective study in the relationship to carcinoma and cardiovascular and metabolic problems. Obstet Gynecol. 1979;54:74–79
- . Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women (The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI Trial). JAMA. 1995;273:199–208
- Prophylaxis of osteoporosis with calcium, estrogens and/or eelcatonin: comparative longitudinal study of bone mass. Maturitas. 1996;23:327–332
- Alendronate and estrogen-progestin in the long-term prevention of bone loss: four-year results from the early postmenopausal intervention cohort study (A randomized, controlled trial). Ann Intern Med. 1999;131:935–942
- . Esterified estrogen therapy in postmenopausal women (Relationships of bone marker changes and plasma estradiol to BMD changes: a two-year study). Menopause. 2000;7:375–382
- Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701–1712
- . NIH and WHI: time for a mea culpa and steps beyond. Menopause. 2007;14:1056–1059
- HRT in the early menopause: scientific evidence and common perceptions (Summary of the First IMS Global Summit on menopause-related issues). http://www.imsociety.org/pdf_files/comments_and_press_statements/ims_press_statement_13_05_08.pdf?SESSID=qr3rsun20036dp70id40v17m87March 29-30, 2008;Accessed June 15, 2008
- . Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet. 2003;362(9382):419–427
- . Evidence from randomised trials on the long-term effects of hormone replacement therapy. Lancet. 2002;360(9337):942–944
- A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med. 2000;133:933–941
- Postmenopausal hormone replacement therapy: scientific review. JAMA. 2002;288:872–881
- Estrogen therapy and coronary-artery calcification. N Engl J Med. 2007;356:2591–2602
- . Association between hormone replacement therapy and subsequent stroke: a meta-analysis. BMJ. 2005;330(7487):342
- . The impact of hormone replacement therapy on quality of life and willingness to pay. Br J Obstet Gynaecol. 1997;104:1191–1195
- . Postmenopausal hormone therapy and quality of life. Int J Gynaecol Obstet. 2006;95:267–271
- . Quality of life and hormone use: new validation results of MRS scale. Health Qual Life Outcomes. 2006;4:32
- . Decade-long use of continuous combined hormone replacement therapy is associated with better health-related quality of life in postmenopausal women, as measured by the generic 15D instrument. J Br Menopause Soc. 2005;11:145–151
- . A 10-year follow-up of postmenopausal women on long-term continuous combined hormone replacement therapy: update of safety and quality-of-life findings. J Br Menopause Soc. 2006;12:115–125
- Postmenopausal hormone replacement therapy for primary prevention of chronic conditions: recommendations and rationale. Ann Intern Med. 2002;137:834–839
- . Amended report from the NAMS Advisory Panel on Postmenopausal Hormone Therapy. Menopause. 2003;10(1):6–12
- Hormone replacement therapy for the primary prevention of chronic diseases: recommendation statement from the Canadian Task Force on Preventive Health Care. CMAJ. 2004;170:1535–1537
- IMS updated recommendations on postmenopausal hormone therapy. Climacteric. 2007;10:181–194
- . Estrogen and progestogen use in peri- and postmenopausal women: March 2007 position statement of The North American Menopause Society. Menopause. 2007;14:168–182
Funding: No research funding.
Conflict of Interest: Dr. Salpeter has consulted in the past with law firms representing Wyeth Pharmaceuticals on issues involving hormone therapy, and was paid on an hourly basis. Dr. Thabane consults with GlaxoSmithKline on statistical and methodological issues. The other authors report no potential conflicts of interest.
Authorship: All authors had access to the data and had a role in writing the manuscript. Edwin Salpeter died after the preparation and approval of the manuscript.
PII: S0002-9343(09)00666-4
doi: 10.1016/j.amjmed.2009.05.021
© 2009 Elsevier Inc. All rights reserved.
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The American Journal of Medicine
Volume 122, Issue 11
, Pages 1016-1022.e1
, November 2009

