The American Journal of Medicine
Volume 122, Issue 12 , Pages 1093-1095 , December 2009

Following the Forgotten Phosphorus

  • Lekshmi T. Nair, MD

      Affiliations

    • Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University Medical Center, Durham, NC
    • ,
  • Leslie Dodd, MD

      Affiliations

    • Department of Pathology, Duke University Medical Center, Durham, NC
    • ,
  • Thomas J. Weber, MD

      Affiliations

    • Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University Medical Center, Durham, NC
    • Corresponding Author InformationRequests for reprints should be addressed to Thomas J. Weber, MD, 08 Baker House, DUMC 3470, Durham, NC 27710

References 

  1. Weidner N, Santa Cruz D. Phosphaturic mesenchymal tumors (A polymorphous group causing osteomalacia or rickets). Cancer. 1987;59:1442–1454
  2. Jan de Beur SM. Tumor-induced osteomalacia. In:  Favus MJ editors. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 5th ed. Washington, DC: American Society for Bone and Mineral Research; 2003;p. 418–422
  3. Berndt T, Kumar R. Phosphatonins and the regulation of phosphate homeostasis. Annu Rev Physiol. 2007;69:341–359
  4. Kronenberg HM. NPT2a—the key to phosphate homeostasis. N Engl J Med. 2002;347:1022–1024
  5. Shimada T, Hasegawa H, Yamazaki Y, et al. FGF-23 is a potent regulator of Vitamin D metabolism and phosphate homeostasis. J Bone Miner Res. 2004;19:429–435
  6. Jan de Beur SM. Tumor-induced osteomalacia. JAMA. 2005;294:1260–1267
  7. Walton RJ, Bijvoet OL. A simple slide-rule method for the assessment of renal tubular reabsorption of phosphate in man. Clin Chim Acta. 1977;81:273–276
  8. Jan de Beur SM, Streeten EA, Civelek AC, et al. Localization of mesenchymal tumors by somatostatin receptor imaging. Lancet. 2002;359:761–763
  9. Nasu T, Kurisu S, Matsuno S, et al. Tumor-induced hypophosphatemic osteomalacia diagnosed by the combinatory procedures of magnetic resonance imaging and venous sampling for FGF23. Intern Med. 2008;47:957–961
  10. Shane E, Parisien M, Henderson JE, et al. Tumor-induced osteomalacia: clinical and basic studies. J Bone Miner Res. 1997;12:1502–1511

 Aimee K. Zaas, MD, Section Editor

 Funding: None required.

 Conflict of Interest: None.

 Authorship: All authors had access to all data and role in writing manuscript.

PII: S0002-9343(09)00625-1

doi: 10.1016/j.amjmed.2009.07.006

The American Journal of Medicine
Volume 122, Issue 12 , Pages 1093-1095 , December 2009

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