The American Journal of Medicine
Volume 122, Issue 8 , Pages 713-723, August 2009

Heart Failure with Preserved Ejection Fraction in Older Adults

  • Michael A. Chen, MD, PhD

      Affiliations

    • Corresponding Author InformationRequests for reprints should be address to Michael A. Chen, MD, PhD, Harborview Medical Center/Cardiology, 325 9th Avenue, Box 359748, Seattle, WA 98104

Division of Cardiology, Harborview Medical Center, University of Washington, Seattle

Abstract 

Age-associated physiologic changes predispose older adults to develop heart failure, even when left ventricular ejection fraction is normal or near normal. Heart failure with a preserved ejection fraction is particularly common in older hypertensive women, and hypertension plays a key role in its pathophysiology. In contrast with heart failure with a reduced ejection fraction, the treatment of heart failure with a preserved ejection fraction has a limited empiric basis, although some basic principles are useful. Ongoing studies provide hope of improving care of these patients.

Keywords: Aging, Diastolic heart failure, Heart failure, Heart failure with preserved ejection fraction

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 Funding: None.

 Conflict of Interest: None.

 Authorship: Author had access to the data and played a role in writing this manuscript.

PII: S0002-9343(09)00397-0

doi:10.1016/j.amjmed.2009.01.038

The American Journal of Medicine
Volume 122, Issue 8 , Pages 713-723, August 2009