Heart Failure with Preserved Ejection Fraction in Older Adults
Abstract
Age-associated physiologic changes predispose older adults to develop heart failure, even when left ventricular ejection fraction is normal or near normal. Heart failure with a preserved ejection fraction is particularly common in older hypertensive women, and hypertension plays a key role in its pathophysiology. In contrast with heart failure with a reduced ejection fraction, the treatment of heart failure with a preserved ejection fraction has a limited empiric basis, although some basic principles are useful. Ongoing studies provide hope of improving care of these patients.
Keywords: Aging, Diastolic heart failure, Heart failure, Heart failure with preserved ejection fraction
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Funding: None.
Conflict of Interest: None.
Authorship: Author had access to the data and played a role in writing this manuscript.
PII: S0002-9343(09)00397-0
doi:10.1016/j.amjmed.2009.01.038
© 2009 Elsevier Inc. All rights reserved.

