Appropriate Antibiotics of Weil Disease

Kittisupamongkol, Weekitt

doi:10.1016/j.amjmed.2009.01.023

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Volume 122, Issue 7 , Page e13, July 2009

Appropriate Antibiotics of Weil Disease

Hua Chiew Hospital, Bangkok, Thailand

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To the Editor:

I read with interest the article by Leung and Schiffer.¹ The authors prescribed a 10-day course of doxycycline in a patient with Weil disease. I disagree. Although doxycycline should be used in mild leptospirosis and chemoprophylaxis, penicillin G or ampicillin administered intravenously is preferred for the treatment of severe leptospirosis or Weil disease.²

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References

Leung J, Schiffer J. Feverish, jaundiced. Am J Med. 2009;122:129–131

Bharti AR, Nally JE, Ricaldi JN, et al. Peru-United States Leptospirosis Consortium (Leptospirosis: a zoonotic disease of global importance). Lancet Infect Dis. 2003;3:757–771