The American Journal of Medicine
Volume 122, Issue 6 , Pages 582.e1-582.e9, June 2009

C-Reactive Protein Elicits White Blood Cell Activation in Humans

  • Radjesh J. Bisoendial, MD, PhD

      Affiliations

    • Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationRequests for reprints should be addressed to Radjesh J. Bisoendial, MD, PhD, Department of Clinical Immunology and Rheumatology, Academic Medical Center, Meibergdreef 9, Room F4-222, 1105 AZ Amsterdam, The Netherlands
  • ,
  • Rakesh S. Birjmohun, MD

      Affiliations

    • Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Fatima Akdim, MD

      Affiliations

    • Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Cornelis van ‘t Veer, PhD

      Affiliations

    • Department of Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • C. Arnold Spek, PhD

      Affiliations

    • Department of Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Daniel Hartman, MD, PhD

      Affiliations

    • deCODE genetics, Reykjavik, Iceland
  • ,
  • Els R. de Groot

      Affiliations

    • Department of Immunopathology, Sanguin Research, Amsterdam, The Netherlands
  • ,
  • Danute M. Bankaitis-Davis, PhD

      Affiliations

    • Source Molecular Diagnostics, Boulder, Colorado
  • ,
  • John J.P. Kastelein, MD, PhD

      Affiliations

    • Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
  • ,
  • Erik S.G. Stroes, MD, PhD

      Affiliations

    • Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands

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 Funding: This work was in part supported by a grant from Pfizer, which had no involvement in the data analysis/interpretation or writing the manuscript. John J. P. Kastelein is an established investigator of The Netherlands Heart Foundation (2000D039).

 Conflict of Interest: None.

 Authorship: All authors had access to the data and played a role in writing.

PII: S0002-9343(09)00116-8

doi:10.1016/j.amjmed.2008.11.032

The American Journal of Medicine
Volume 122, Issue 6 , Pages 582.e1-582.e9, June 2009