The American Journal of Medicine
Volume 122, Issue 3 , Pages 290-300 , March 2009

Combination Therapy Versus Monotherapy in Reducing Blood Pressure: Meta-analysis on 11,000 Participants from 42 Trials

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 Funding: None.

 Conflict of Interest: Nicholas J. Wald and Malcolm Law hold patents (EU1272220 and GB2361186) for a combination pill for the prevention of cardiovascular disease (Polypill) and together with David Wald have interests in its development.

 Authorship: All authors had access to the data and played a role in writing this manuscript.

PII: S0002-9343(08)00992-3

doi: 10.1016/j.amjmed.2008.09.038

The American Journal of Medicine
Volume 122, Issue 3 , Pages 290-300 , March 2009