The American Journal of Medicine
Volume 122, Issue 3 , Pages 257-264 , March 2009

Prognostic Value of ECG Among Patients with Acute Pulmonary Embolism and Normal Blood Pressure

References 

  1. Tapson VF. Acute pulmonary embolism. N Engl J Med. 2008;358:1037–1052
  2. Kasper W, Konstantinides S, Geibel A, et al. Prognostic significance of right ventricular afterload stress detected by echocardiography in patients with clinically suspected pulmonary embolism. Heart. 1997;77:346–349
  3. Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet. 1999;353:1386–1389
  4. Grifoni S, Olivotto I, Cecchini P, et al. Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction. Circulation. 2000;101:2817–2822
  5. Kucher N, Rossi E, De Rosa M, Goldhaber SZ. Prognostic role of echocardiography among patients with acute pulmonary embolism and a systolic arterial pressure of 90 mm Hg or higher. Arch Intern Med. 2005;165:1777–1781
  6. Iles S, Le Heron CJ, Davies G, et al. ECG score predicts those with the greatest percentage of perfusion defects due to acute pulmonary thromboembolic disease. Chest. 2004;125:1651–1656
  7. Kucher N, Walpoth N, Wustmann K, et al. QR in V1 an ECG sign associated with right ventricular strain and adverse clinical outcome in pulmonary embolism. Eur Heart J. 2003;24:1113–1119
  8. Punukollu G, Gowda RM, Vasavada B, et al. Role of electrocardiography in identifying right ventricular dysfunction in acute pulmonary embolism. Am J Cardiol. 2005;96:450–452
  9. Daniel KR, Courtney DM, Kline JA. Assessment of cardiac stress from massive pulmonary embolism with 12-lead ECG. Chest. 2001;120:474–481
  10. Geibel A, Zehender M, Kasper W, et al. Prognostic value of the ECG on admission in patients with acute major pulmonary embolism. Eur Respir J. 2005;25:843–848
  11. Wan S, Quinlan DJ, Agnelli G, Eikelboom JW. Thrombolysis compared with heparin for the initial treatment of pulmonary embolism: a meta-analysis of the randomized controlled trials. Circulation. 2004;110:744–749
  12. Hyers TM, Agnelli G, Hull RD, et al. Sixth ACCP Consensus Conference on antithrombotic therapy (Antithrombotic therapy for venous thromboembolic disease). Chest. 2001;119:176S–193S
  13. Cox DR. Regression models and life tables (with discussion). J R Statist Soc B. 1972;34:187–220
  14. Manganelli D, Palla A, Donnamaria V, Giuntini C. Clinical features of pulmonary embolism (Doubts and certainties). Chest. 1995;107(1 Suppl):25S–32S
  15. Richman PB, Loutfi H, Lester SJ, et al. Electrocardiographic findings in emergency department patients with pulmonary embolism. J Emerg Med. 2004;27:121–126
  16. Kosuge M, Kimura K, Ishikawa T, et al. Prognostic significance of inverted T waves in patients with acute pulmonary embolism. Circ J. 2006;70:750–755
  17. Task Force on Pulmonary Embolism, European Society of Cardiology. Guidelines on diagnosis and management of acute pulmonary embolism. Eur Heart J. 2000;21:1301–1336
  18. British Thoracic Society guidelines for the management of suspected acute pulmonary embolism. Thorax. 2003;58:470–483
  19. Binder L, Pieske B, Olschewski M, et al. N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation. 2005;112:1573–1579
  20. Konstantinides S, Geibel A, Heusel G, et al. Management Strategies and Prognosis of Pulmonary Embolism-3 Trial Investigators Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. N Engl J Med. 2002;347:1143–1150
  21. Meyer T, Binder L, Hruska N, et al. Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol. 2000;36:1632–1636
  22. Kucher N, Goldhaber SZ. Cardiac biomarkers for risk stratification of patients with acute pulmonary embolism. Circulation. 2003;108:2191–2194
  23. Kucher N, Wallmann D, Carone A, et al. Incremental prognostic value of troponin I and echocardiography in patients with acute pulmonary embolism. Eur Heart J. 2003;24:1651–1656

 Funding: None.

 Conflict of Interest: None of the authors have any conflicts of interest associated with the work presented in this manuscript.

 Authorship: All authors had access to the data and played a role in writing this manuscript.

PII: S0002-9343(08)00991-1

doi: 10.1016/j.amjmed.2008.08.031

The American Journal of Medicine
Volume 122, Issue 3 , Pages 257-264 , March 2009