The American Journal of Medicine
Volume 122, Issue 2 , Pages 107-108 , February 2009

Risk Stratification in Non-ST-segment Elevation Acute Coronary Syndromes: Troponin Alone Is not Enough

  • Philippe Gabriel Steg

      Affiliations

    • Inserm U-698, Université Paris 7 and Assistance Publique-Hôpitaux de Paris, Paris, France
  • ,
  • Gordon FitzGerald

      Affiliations

    • Center for Outcomes Research, University of Massachusetts, Worcester, Mass
  • ,
  • Keith A.A. Fox

      Affiliations

    • University of Edinburgh, Edinburgh, UK

  • Image Result

    The bar chart describes the distribution of (left axis) troponin positive (white bars) and troponin negative (black bars) patients according to category of GRACE risk score (ranging from <51 to >226)

    The bar chart describes the distribution of (left axis) troponin positive (white bars) and troponin negative (black bars) patients according to category of GRACE risk score (ranging from <51 to >226) among 27,406 patients with non-ST-segment elevation acute coronary syndromes in the GRACE registry. The black curve (right axis) depicts the observed hospital mortality rates.

 Funding: The GRACE registry is funded by a research grant from sanofi-aventis.

 Conflict of interest: Dr. Steg reports having received honoraria as speaker or consultant from Astellas, AstraZeneca, Bayer, Boehringer-Ingelheim, BMS, Endotis, GSK, Medtronic, MSD, Nycomed, sanofi-aventis, Servier, The Medicines Company. In addition, his institution has received a research grant from sanofi-aventis in the past 7 years. Dr. FitzGerald has no disclosures. Dr. Fox reports having received honoraria as speaker or consultant and research grants from Sanofi-aventis, GSK and Merck, Sharpe and Dohme.

 Authorship: All authors had access to the data and a role in writing the manuscript.

PII: S0002-9343(08)00972-8

doi: 10.1016/j.amjmed.2008.07.029

The American Journal of Medicine
Volume 122, Issue 2 , Pages 107-108 , February 2009