The American Journal of Medicine
Volume 122, Issue 2 , Pages 152-161 , February 2009

The Impact of Revascularization on Mortality in Patients with Nonacute Coronary Artery Disease

  • Allen Jeremias, MD, MSc

      Affiliations

    • Department of Medicine (Cardiovascular Medicine), Stony Brook University Medical Center, Stony Brook, NY
  • ,
  • Sanjay Kaul, MD

      Affiliations

    • Division of Cardiology, Cedars-Sinai Medical Center and David Geffen School of Medicine, University of California, Los Angeles, Calif
  • ,
  • Todd K. Rosengart, MD

      Affiliations

    • Department of Surgery (Cardiothoracic Surgery), Stony Brook University Medical Center, Stony Brook, NY
  • ,
  • Luis Gruberg, MD

      Affiliations

    • Department of Medicine (Cardiovascular Medicine), Stony Brook University Medical Center, Stony Brook, NY
  • ,
  • David L. Brown, MD

      Affiliations

    • Department of Medicine (Cardiovascular Medicine), Stony Brook University Medical Center, Stony Brook, NY
    • Corresponding Author InformationRequests for reprints should be addressed to David L. Brown, MD, Division of Cardiovascular Medicine, State University of New York-Stony Brook School of Medicine, Health Sciences Center T16-080, Stony Brook, NY 11794

  • Image Result

    Comparison of coronary revascularization versus medical therapy for overall mortality. All included studies are shown by name along with point estimates of the OR and respective 95% CIs. The size of t

    Comparison of coronary revascularization versus medical therapy for overall mortality. All included studies are shown by name along with point estimates of the OR and respective 95% CIs. The size of the squares denoting the point estimate in each study is proportional to the weight of the study. The study by Hambrecht et al27 is not included because there were no mortalities in either the revascularization or medical therapy groups.

  • Image Result
    Cumulative OR for overall mortality with coronary revascularization versus medical therapy.

    Cumulative OR for overall mortality with coronary revascularization versus medical therapy.

  • Image Result
    Comparison of coronary revascularization versus medical therapy for overall mortality, stratified by revascularization modality: coronary artery bypass surgery (A) and percutaneous coronary interventi

    Comparison of coronary revascularization versus medical therapy for overall mortality, stratified by revascularization modality: coronary artery bypass surgery (A) and percutaneous coronary intervention (B). Interpretation of OR plot as in Figure 1.

  • Image Result
    Comparison of coronary revascularization versus medical therapy for nonfatal myocardial infarction. Interpretation of OR plot as in Figure 1.

    Comparison of coronary revascularization versus medical therapy for nonfatal myocardial infarction. Interpretation of OR plot as in Figure 1.

 Funding: None.

 Conflict of Interest: None of the authors have any conflicts of interest associated with the work presented in this article.

 Authorship: All authors had access to the data and were involved as follows: Conception (AJ, TKR, LG, DLB); statistical analysis (AJ, SK, DLB); writing of article (AJ, DLB); critical review (AJ, SK, TKR, LG, DLB).

PII: S0002-9343(08)00955-8

doi: 10.1016/j.amjmed.2008.07.027

The American Journal of Medicine
Volume 122, Issue 2 , Pages 152-161 , February 2009