The American Journal of Medicine
Volume 121, Issue 11 , Pages 931-932 , November 2008

Are Oral Sodium Phosphate Products for Bowel Cleansing Safe for the General Population?

References 

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  2. Sica DA, Carl D, Zfass AM. Acute phosphate nephropathy—an emerging issue. Am J Gastroenterol. 2007;102:1844–1847
  3. Markowitz GS, Nasr SH, Klein P, et al. Renal failure due to acute nephrocalcinosis following oral sodium phosphate bowel cleansing. Hum Pathol. 2004;35:675–684
  4. Desmeules S, Bergeron MJ, Isenring P. Acute phosphate nephropathy and renal failure. N Engl J Med. 2003;349:1006–1007
  5. Wexner SD, Beck DE, Baron TH, et al. A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Surg Endosc. 2006;20:1147–1160
  6. Russmann S, Lamerato L, Marfatia A, et al. Risk of impaired renal function after colonoscopy: a cohort study in patients receiving either oral sodium phosphate or polyethylene glycol. Am J Gastroenterol. 2007;102:2655–2663
  7. Singal AK, Rosman AS, Post JB, et al. The renal safety of bowel preparations for colonoscopy: a comparative study of oral sodium phosphate solution and polyethylene glycol. Aliment Pharmacol Ther. 2008;27:41–47
  8. Hurst FP, Bohen EM, Osgard EM, et al. Association of oral sodium phosphate purgative use with acute kidney injury. J Am Soc Nephrol. 2007;18:3192–3198
  9. Brunelli SM, Lewis JD, Gupta M, et al. Risk of kidney injury following oral phosphosoda bowel preparations. J Am Soc Nephrol. 2007;18:3199–3205
  10. Harkonen S, Kjellstrand C. Contrast nephropathy. Am J Nephrol. 1981;1:69–77
  11. Khurana A, McLean L, Atkinson S, Foulks CJ. The effect of oral sodium phosphate drug products on renal function in adults undergoing bowel endoscopy. Arch Intern Med. 2008;168:593–597
  12. DiPalma JA, Buckley SE, Warner BA, Culpepper RM. Biochemical effects of oral sodium phosphate. Dig Dis Sci. 1996;41:749–753
  13. Murer H, Hernando N, Forster I, Biber J. Regulation of Na/Pi transporter in the proximal tubule. Annu Rev Physiol. 2003;65:531–542
  14. Patel V, Emmett M, Santa Ana CA, Fordtran JS. Pathogenesis of nephrocalcinosis after sodium phosphate catharsis to prepare for colonoscopy: intestinal phosphate absorption and its effect on urine mineral and electrolyte excretion. Hum Pathol. 2007;38:193–195

PII: S0002-9343(08)00758-4

doi: 10.1016/j.amjmed.2008.07.018

The American Journal of Medicine
Volume 121, Issue 11 , Pages 931-932 , November 2008

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