The American Journal of Medicine
Volume 121, Issue 11 , Pages 997-1001 , November 2008

Clinical Outcome of Patients with Heart Failure and Preserved Left Ventricular Function

  • Israel Gotsman, MD

      Affiliations

    • Heart Institute, Hadassah University Hospital, Jerusalem, Israel
    • Corresponding Author InformationRequests for reprints should be addressed to Israel Gotsman, MD, Heart Institute, Hadassah University Hospital, POB 12000, Jerusalem, Israel IL-91120
    • ,
  • Donna Zwas, MD

      Affiliations

    • Heart Institute, Hadassah University Hospital, Jerusalem, Israel
    • ,
  • David Planer, MD

      Affiliations

    • Heart Institute, Hadassah University Hospital, Jerusalem, Israel
    • ,
  • Tanya Azaz-Livshits, PhD

      Affiliations

    • Department of Clinical Pharmacology, Hadassah University Hospital, Jerusalem, Israel
    • ,
  • Dan Admon, MD

      Affiliations

    • Heart Institute, Hadassah University Hospital, Jerusalem, Israel
    • ,
  • Chaim Lotan, MD

      Affiliations

    • Heart Institute, Hadassah University Hospital, Jerusalem, Israel
    • ,
  • Andre Keren, MD

      Affiliations

    • Heart Institute, Hadassah University Hospital, Jerusalem, Israel

References 

  1. Owan TE, Hodge DO, Herges RM, et al. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med. 2006;355:251–259
  2. Bhatia RS, Tu JV, Lee DS, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med. 2006;355:260–269
  3. Bursi F, Weston SA, Redfield MM, et al. Systolic and diastolic heart failure in the community. JAMA. 2006;296:2209–2216
  4. Tribouilloy C, Rusinaru D, Mahjoub H, et al. Prognosis of heart failure with preserved ejection fraction: a 5 year prospective population-based study. Eur Heart J. 2008;29:339–347Epub 2007 Dec 22
  5. Berry C, Hogg K, Norrie J, et al. Heart failure with preserved left ventricular systolic function: a hospital cohort study. Heart. 2005;91:907–913
  6. Varela-Roman A, Grigorian L, Barge E, et al. Heart failure in patients with preserved and deteriorated left ventricular ejection fraction. Heart. 2005;91:489–494
  7. Lenzen MJ, Scholte op Reimer WJ, et al. Differences between patients with a preserved and a depressed left ventricular function: a report from the EuroHeart Failure Survey. Eur Heart J. 2004;25:1214–1220
  8. Masoudi FA, Havranek EP, Smith G, et al. Gender, age, and heart failure with preserved left ventricular systolic function. J Am Coll Cardiol. 2003;41:217–223
  9. Gustafsson F, Torp-Pedersen C, Brendorp B, et al. Long-term survival in patients hospitalized with congestive heart failure: relation to preserved and reduced left ventricular systolic function. Eur Heart J. 2003;24:863–870
  10. Fonarow GC, Stough WG, Abraham WT, et al. Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry. J Am Coll Cardiol. 2007;50:768–777
  11. Tsutsui H, Tsuchihashi M, Takeshita A. Mortality and readmission of hospitalized patients with congestive heart failure and preserved versus depressed systolic function. Am J Cardiol. 2001;88:530–533
  12. Zile MR, Gaasch WH, Carroll JD, et al. Heart failure with a normal ejection fraction: is measurement of diastolic function necessary to make the diagnosis of diastolic heart failure?. Circulation. 2001;104:779–782
  13. Yusuf S, Pfeffer MA, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362:777–781
  14. Lonn E, Shaikholeslami R, Yi Q, et al. Effects of ramipril on left ventricular mass and function in cardiovascular patients with controlled blood pressure and with preserved left ventricular ejection fraction: a substudy of the Heart Outcomes Prevention Evaluation (HOPE) Trial. J Am Coll Cardiol. 2004;43:2200–2206
  15. Lewis BS, Shotan A, Gottlieb S, et al. Late mortality and determinants in patients with heart failure and preserved systolic left ventricular function: the Israel Nationwide Heart Failure Survey. Isr Med Assoc J. 2007;9:234–238
  16. Solomon SD, Anavekar N, Skali H, et al. Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients. Circulation. 2005;112:3738–3744
  17. Smith GL, Masoudi FA, Vaccarino V, et al. Outcomes in heart failure patients with preserved ejection fraction: mortality, readmission, and functional decline. J Am Coll Cardiol. 2003;41:1510–1518

 Funding source: The Louis Chor Memorial Trust Award for research in Cardiac Disease.

 Conflict of interest statement for all authors: There is no conflict of interests.

 Authorship: The work is original and all authors meet the criteria for authorship, including acceptance of responsibility for the scientific content of the article. All authors had access to the data and a role in writing the article.

PII: S0002-9343(08)00705-5

doi: 10.1016/j.amjmed.2008.06.031

The American Journal of Medicine
Volume 121, Issue 11 , Pages 997-1001 , November 2008

Article Tools

* Image Usage & Resolution