Early Sustained Ventricular Arrhythmias Complicating Acute Myocardial Infarction^⁎

Independent predictors of sustained ventricular arrhythmias identified via multivariable logistic regression after adjustment for age, race, diabetes, hypertension, aortoiliac disease, chronic kidney disease, chronic obstructive pulmonary disease, congestive heart failure, cardiogenic shock, left ventricular ejection fraction, MI within 6 hours, left circumflex artery stenosis, proximal left anterior descending artery stenosis, and left main coronary artery disease. OR=odds ratio; CI=confidence interval; LCX=left circumflex; EF=ejection fraction; MI=myocardial infarction.

Incidence of sustained VT/VF and in-hospital mortality according to the number of readily identifiable risk factors* on presentation that had a P value <.1 in univariate analysis and subsequently identified through stepwise logistic regression.*Risk factors were chronic kidney disease, left ventricular ejection fraction<40%, cardiogenic shock, heart failure during admission, and presentation within 6 hours. (Note, n=7310 for this analysis, because we only included those patients with a known ejection fraction.) VT/VF=ventricular tachycardia/ventricular fibrillation.

In-hospital mortality according to successful percutaneous intervention in those patients with and without sustained ventricular arrhythmia. Log-linear analysis identified a significant interaction among sustained VT/VF, successful percutaneous coronary intervention, and in-hospital mortality (3-way P <.001). Successful percutaneous coronary intervention was associated with decreased mortality (2-way P <.001), and sustained VT/VF was associated with increased mortality (2-way P <.001). There was no difference in the rates of angiographic success in those with and without sustained VT/VF (2-way P=not significant). PCI=percutaneous coronary intervention; VT/VF=ventricular tachycardia/ventricular fibrillation.