The American Journal of Medicine
Volume 121, Issue 12 , Pages 1052-1054 , December 2008

Withering Away

  • Zachary D. Goldberger, MD

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Zachary D. Goldberger, MD, University of Michigan Health System, Division of Cardiovascular Medicine, Cardiovascular Center, 1500 East Medical Center Drive SPC 5853, Ann Arbor, MI 48109

References 

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  2. Demiryurek AT, Demiryurek S. Cardiotoxicity of digitalis glycosides: roles of autonomic pathways, autacoids and ion channels. Auton Autacoid Pharmacol. 2005;25:35–52
  3. Hauptman PJ, Kelly RA. Digitalis. Circulation. 1999;99:1265–1270
  4. Ma G, Brady WJ, Pollack M, Chan TC. Electrocardiographic manifestations: digitalis toxicity. J Emerg Med. 2001;20:145–152
  5. Hager WD, Fenster P, Mayersohn M, et al. Digoxin-quinidine interaction Pharmacokinetic evaluation. N Engl J Med. 1979;300:1238–1241
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  7. Singh BN. Amiodarone: the expanding antiarrhythmic role and how to follow a patient on chronic therapy. Clin Cardiol. 1997;20:608–618
  8. Rathore SS, Curtis JP, Wang Y, et al. Association of serum digoxin concentration and outcomes in patients with heart failure. JAMA. 2003;289:871–878
  9. Ahmed A. Digoxin and reduction in mortality and hospitalization in geriatric heart failure: importance of low doses and low serum concentrations. J Gerontol A Biol Sci Med Sci. 2007;62:323–329
  10. Gheorghiade M, van Veldhuisen DJ, Colucci WS. Contemporary use of digoxin in the management of cardiovascular disorders. Circulation. 2006;113:2556–2564
  11. Ahmed A, Young JB, Gheorghiade M. The underuse of digoxin in heart failure, and approaches to appropriate use. CMAJ. 2007;176:641–643

 Julia H. Indik, MD, PhD, Section Editor

 Conflict of interest: There are no conflicts of interest or financial disclosures.

PII: S0002-9343(08)00351-3

doi: 10.1016/j.amjmed.2008.04.006

The American Journal of Medicine
Volume 121, Issue 12 , Pages 1052-1054 , December 2008

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