The American Journal of Medicine
Volume 121, Issue 6, Supplement , Pages S1-S2 , June 2008

Introduction

  • Jeff Unger, MD

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Jeff Unger, MD, Chino Medical Group Diabetes and Headache Intervention Center, 5475 Walnut Avenue, Chino, California 91710.

References 

  1. Harris MI, Flegal KM, Cowie CC, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults: the Third National Health and Nutrition Examination Survey, 1988–1994. Diabetes Care. 1998;21:518–524
  2. Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977–986
  3. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837–853
  4. Ohkubo Y, Kishikawa H, Araki E, et al. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes: a randomized prospective 6-year study. Diabetes Res Clin Pract. 1995;28:103–117
  5. DCCT/EDIC Research Group. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med. 2000;342:381–389
  6. ACE/AACE Diabetes Recommendations Implementation Conference. Road map for the prevention and treatment of type 2 diabetes. http://www.aace.com/meetings/consensus/odimplementation/roadmap.pdfAccessed April 22, 2007
  7. American Diabetes Association. Clinical practice recommendations. Diabetes Care. 2007;230(suppl 1):S9–S10
  8. Holman RR, Thorne KI, Farmer AJ, et al. 4-T Study Group Addition of biphasic, prandial, or basal insulin to oral therapy in type 2 diabetes. N Engl J Med. 2007;357:1716–1730
  9. Unger J. Physiologic insulin replacement therapy. In: Diabetes Management In Primary Care. Philadelphia: Lippincott, Williams & Wilkins; 2007;p. 192–264

 Statement of author disclosure: Please see the Author Disclosures section at the end of this article.

PII: S0002-9343(08)00307-0

doi: 10.1016/j.amjmed.2008.03.020

The American Journal of Medicine
Volume 121, Issue 6, Supplement , Pages S1-S2 , June 2008

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