The American Journal of Medicine
Volume 121, Issue 5 , Pages 406-418 , May 2008

Association Between Alcohol Consumption and Both Osteoporotic Fracture and Bone Density

  • Karina M. Berg, MD, MS

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Corresponding Author InformationRequests for reprints should be addressed to Karina M. Berg, MD, MS, Montefiore Medical Center, Division of General Internal Medicine, 111 East 210th Street, Bronx, NY 10467.
    • ,
  • Hillary V. Kunins, MD, MS, MPH

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • ,
  • Jeffrey L. Jackson, MD, MPH

      Affiliations

    • Uniformed Services University, Bethesda, Md
    • ,
  • Shadi Nahvi, MD

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • ,
  • Amina Chaudhry, MD, MPH

      Affiliations

    • Johns Hopkins University, Baltimore, Md.
    • ,
  • Kenneth A. Harris Jr, MD, PhD

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • ,
  • Rubina Malik, MD, MS

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • ,
  • Julia H. Arnsten, MD, MPH

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Department of Epidemiology and Population Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY
    • Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY

  • Image Result

    Study selection process. Studies may be excluded for multiple reasons.

    Study selection process. Studies may be excluded for multiple reasons.

  • Image Result

    Association between alcohol consumption and hip fracture risk. Reference exposure is zero drinks per day. Size of data marker represents sample size. Horizontal lines denote 95% confidence intervals.

    Association between alcohol consumption and hip fracture risk. Reference exposure is zero drinks per day. Size of data marker represents sample size. Horizontal lines denote 95% confidence intervals.

  • Image Result

    Association between alcohol consumption and adjusted femoral neck bone mineral density. Adjustment for confounders is variable. Study adjusting for the fewest covariates controlled for age, smoking, w

    Association between alcohol consumption and adjusted femoral neck bone mineral density. Adjustment for confounders is variable. Study adjusting for the fewest covariates controlled for age, smoking, weight, and height. Study adjusting for the most covariates also controlled for leisure time physical activity, difficulty arising from a bed or chair, estrogen therapy, thiazide-type diuretics, thyroid agents, race, diabetes, hypertension, cardiovascular disease, visual problems, arthritis, previous cancer, weight in early teens, and Mini-Mental Status Exam score.

 This study was funded by the Program of Research Integrating Substance Use in Mainstream Healthcare with support from the Robert Wood Johnson Foundation, National Institute on Drug Abuse (NIDA), and National Institute on Alcohol Abuse and Alcoholism (co-directors A. T. McLellan, PhD, and B. J. Turner, MD, MSEd). Additional support was provided by grants K23 DA021087 from the NIDA and the National Institute of Mental Health and a Robert Wood Johnson Foundation Physician Faculty Scholar Award to Dr Berg; grants R25 DA14551 and R01 DA015302 from the NIDA to Dr Arnsten; and a Center for AIDS Research grant (P30 AI51519) to the Albert Einstein College of Medicine of Yeshiva University from the National Institutes of Health.

PII: S0002-9343(08)00109-5

doi: 10.1016/j.amjmed.2007.12.012

The American Journal of Medicine
Volume 121, Issue 5 , Pages 406-418 , May 2008

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