The American Journal of Medicine
Volume 121, Issue 2 , Pages 98-104, February 2008

Abnormalities in Glucose Metabolism in Patients with Schizophrenia Treated with Atypical Antipsychotic Medications

  • Alan N. Elias, MD

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Alan N. Elias, MD, University of California, Irvine Medical Center, 101 The City Drive South, Orange, CA 92868.
    • ,
  • Heather Hofflich, DO

The University of California, Irvine, Medical Center, Orange.

Abstract 

The incidence of carbohydrate intolerance and overt diabetes is increased in patients with schizophrenia treated with the newer atypical antipsychotic agents. The precise mechanism for these abnormalities remains obscure. This review examines the potential interaction between atypical antipsychotic medications and several hormones known to influence appetite regulation and carbohydrate metabolism.

Keywords: Atypical antipsychotic agents, Carbohydrate intolerance, Diabetes, Schizophrenia

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PII: S0002-9343(07)00935-7

doi:10.1016/j.amjmed.2007.08.036

The American Journal of Medicine
Volume 121, Issue 2 , Pages 98-104, February 2008

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