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The American Journal of Medicine
Volume 120, Issue 10,
Supplement 2
, Pages S18-S25
, October 2007
Outpatient Management of Stable Acute Pulmonary Embolism: Proposed Accelerated Pathway for Risk Stratification
References
- . The epidemiology of venous thromboembolism. Circulation. 2003;107(suppl 1):I4–I18
- Systematic lung scans reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. Arch Intern Med. 2000;160:159–164
- . Clinical practice: treatment of deep-vein thrombosis. N Engl J Med. 2004;351:268–277
- . Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(suppl 3):401S–428S
- . Estimated annual number of incident and recurrent, non-fatal and fatal venous thromboembolism (VTE) events in the US. [abstract] Blood. 2005;102
- . Clinical suspicion of fatal pulmonary embolism. Chest. 2001;120:791–795
- . Prevalence of acute pulmonary embolism among patients in a general hospital and at autopsy. Chest. 1995;108:978–981
- . Pulmonary embolism in medical patients: improved diagnosis and the role of low-molecular-weight heparin in prevention and treatment. J Thromb Thrombolysis. 2004;18:117–125
- . Prognosis in pulmonary embolism. Curr Opin Pulm Med. 2001;7:354–359
- . Major pulmonary embolism: review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism. Chest. 2002;121:877–905
- . Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet. 1999;353:1386–1389
- . Right ventricular dysfunction secondary to acute massive pulmonary embolism detected by helical computed tomography pulmonary angiography. Clin Imaging. 2005;29:16–21
- Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med. 2005;172:1041–1046
- . Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study. Arch Intern Med. 1999;159:445–453
- Validation of a risk score identifying patients with acute pulmonary embolism, who are at low risk of clinical adverse outcome. Thromb Haemost. 2004;91:1232–1236
- . Predicting adverse outcome in patients with acute pulmonary embolism: a risk score. Thromb Haemost. 2000;84:548–552
- . Patent foramen ovale is an important predictor of adverse outcome in patients with major pulmonary embolism. Circulation. 1998;97:1946–1951
- . Echocardiography in the management of pulmonary embolism. Ann Intern Med. 2002;136:691–700
- . Acute pulmonary embolism: part II (Risk stratification, treatment, and prevention). Circulation. 2003;108:2834–2838
- . Prognostic role of echocardiography among patients with acute pulmonary embolism and a systolic arterial pressure of 90 mm Hg or higher. Arch Intern Med. 2005;165:1777–1781
- Right ventricular enlargement on chest computed tomography: prognostic role in acute pulmonary embolism. Circulation. 2004;109:2401–2404
- . Right ventricular enlargement on chest computed tomography: a predictor of early death in acute pulmonary embolism. Circulation. 2004;110:3276–3280
- Right ventricular dysfunction and pulmonary obstruction index at helical CT: prediction of clinical outcome during 3-month follow-up in patients with acute pulmonary embolism. Radiology. 2005;235:798–803
- N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation. 2005;112:1573–1579
- Biomarker-based risk assessment model in acute pulmonary embolism. Eur Heart J. 2005;26:2166–2172
- . Low pro-brain natriuretic peptide levels predict benign clinical outcome in acute pulmonary embolism. Circulation. 2003;107:1576–1578
- Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction. Circulation. 2000;101:2817–2822
- . Echocardiography Doppler in pulmonary embolism: right ventricular dysfunction as a predictor of mortality rate. Am Heart J. 1997;134:479–487
- . Cardiac biomarkers for risk stratification of patients with acute pulmonary embolism. Circulation. 2003;108:2191–2194
- . Prognostic value of the ECG on admission in patients with acute major pulmonary embolism. Eur Respir J. 2005;25:843–848
- Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation. 2000;102:211–217
- . Cardiac troponin I elevation in acute pulmonary embolism is associated with right ventricular dysfunction. J Am Coll Cardiol. 2000;36:1632–1636
- Increased brain natriuretic peptide as a marker for right ventricular dysfunction in acute pulmonary embolism. Thromb Haemost. 2001;86:1193–1196
- Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism. Circulation. 2002;106:1263–1268
- . Clinical usefulness and prognostic value of elevated cardiac troponin I levels in acute pulmonary embolism. Am Heart J. 2003;145:821–825
- Cardiac troponin T monitoring identifies high-risk group of normotensive patients with acute pulmonary embolism. Chest. 2003;123:1947–1952
- . Release kinetics of cardiac troponin T in survivors of confirmed severe pulmonary embolism. Clin Chem. 2002;48:673–675
- . Acute pulmonary embolism: part II (Treatment and prophylaxis). Circulation. 2006;114:e42–e47
- . Applying the grades of recommendation for antithrombotic and thrombolytic therapy: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(suppl 3):179S–187S
- . Guidelines on diagnosis and management of acute pulmonary embolism. Eur Heart J. 2000;21:1301–1336
- . Treating thrombosis in the 21st century. N Engl J Med. 2003;349:1762–1764
- Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest. 2001;119(suppl 1):64S–94S
- Expanding eligibility for outpatient treatment of deep venous thrombosis and pulmonary embolism with low-molecular-weight heparin: a comparison of patient self-injection with homecare injection. Arch Intern Med. 1998;158:1809–1812
- . Outpatient treatment of pulmonary embolism with dalteparin. Thromb Haemost. 2000;83:209–211
- . Could deep vein thrombosis be safely treated at home?. Bratisl Lek Listy. 2001;102:458–461
- . Outpatient treatment of pulmonary embolism is feasible and safe in a substantial proportion of patients. J Thromb Haemost. 2003;1:186–187
- Outpatient management of pulmonary embolism: results from the national multicentre PE study. [abstract] Blood. 2005;106:911
- Outpatient tinzaparin therapy in pulmonary embolism quantified with ventilation/perfusion scintigraphy. Med Sci Monit. 2006;12:PI9–PI3
- . A pharmacologic overview of current and emerging anticoagulants. Cleve Clin J Med. 2005;72(suppl 1):S2–S6
- . Heparin-induced thrombocytopenia associated with fondaparinux. N Engl J Med. 2007;356:2653–2655
- Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. N Engl J Med. 2003;349:1695–1702
- . Clinical and economic aspects of managing venous thromboembolism in the outpatient setting. Semin Hematol. 2001;38:58–66
- . Outpatient treatment of patients with deep-vein thrombosis or pulmonary embolism. Curr Opin Pulm Med. 2001;7:360–364
- . Outpatient treatment of patients with pulmonary embolism. Semin Vasc Med. 2001;1:229–234
- Outpatient therapy with low molecular weight heparin for the treatment of venous thromboembolism: a review of efficacy, safety, and costs. Am J Med. 2003;115:298–308
- . Management of pulmonary embolism in the home. Med J Aust. 2005;183:239–242
- A randomized trial comparing 2 low-molecular-weight heparins for the outpatient treatment of deep vein thrombosis and pulmonary embolism. Arch Intern Med. 2005;165:733–738
- Treatment of venous thrombosis with intravenous unfractionated heparin administered in the hospital as compared with subcutaneous low-molecular-weight heparin administered at home. N Engl J Med. 1996;334:682–687
- . Initial outpatient treatment of venous thromboembolism with fondaparinux: the MATISSE trials. In: Poster presented at the Annual Meeting of The International Society on Thrombosis and Haemostasis. August 6, Sydney, Australia. 2005;
- . Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolism. Chest. 2005;128:1601–1610
- . The outpatient treatment of deep vein thrombosis delivers cost savings to patients and their families, compared to inpatient therapy. Thromb Res. 2003;112:13–18
- Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial. Ann Intern Med. 2004;140:867–873
Please see the Conflict of Interest section at the end of this article.
PII: S0002-9343(07)00740-1
doi: 10.1016/j.amjmed.2007.08.010
© 2007 Elsevier Inc. All rights reserved.
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The American Journal of Medicine
Volume 120, Issue 10,
Supplement 2
, Pages S18-S25
, October 2007

