The American Journal of Medicine
Volume 120, Issue 8 , Pages 700-705 , August 2007

Death and Disability from Warfarin-Associated Intracranial and Extracranial Hemorrhages

  • Margaret C. Fang, MD, MPH

      Affiliations

    • The Department of Medicine, University of California, San Francisco, Calif
    • Corresponding Author InformationRequests for reprints should be addressed to Margaret C. Fang, MD, MPH, Department of Medicine, Hospitalist Group, University of California, San Francisco, 533 Parnassus Ave, Box 0131, San Francisco, CA 94143.
    • ,
  • Alan S. Go, MD

      Affiliations

    • The Department of Medicine, University of California, San Francisco, Calif
    • Department of Epidemiology and Biostatistics, University of California, San Francisco, Calif
    • Division of Research, Kaiser Permanente of Northern California, Oakland, Calif
    • ,
  • Yuchiao Chang, PhD

      Affiliations

    • Clinical Epidemiology Unit, Massachusetts General Hospital, Boston, Mass
    • ,
  • Elaine M. Hylek, MD, MPH

      Affiliations

    • General Internal Medicine and Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Mass.
    • ,
  • Lori E. Henault, MPH

      Affiliations

    • General Internal Medicine and Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Mass.
    • ,
  • Nancy G. Jensvold, MPH

      Affiliations

    • Division of Research, Kaiser Permanente of Northern California, Oakland, Calif
    • ,
  • Daniel E. Singer, MD

      Affiliations

    • Clinical Epidemiology Unit, Massachusetts General Hospital, Boston, Mass

  • Image Result

    Risk of death 30 days after hospitalization for warfarin-associated intracranial hemorrhage versus major extracranial hemorrhage; 95% confidence intervals (CIs) (vertical bars). P value refers to the

    Risk of death 30 days after hospitalization for warfarin-associated intracranial hemorrhage versus major extracranial hemorrhage; 95% confidence intervals (CIs) (vertical bars). P value refers to the chi-square comparison of mortality rate of intracranial versus extracranial hemorrhage.

  • Image Result
    Functional deficit at the time of discharge resulting from warfarin-associated intracranial hemorrhage versus major extracranial hemorrhage in hospitalized patients with atrial fibrillation. P value r

    Functional deficit at the time of discharge resulting from warfarin-associated intracranial hemorrhage versus major extracranial hemorrhage in hospitalized patients with atrial fibrillation. P value refers to chi-square comparison of discharge deficit between intracranial and extracranial hemorrhage events. Analysis excludes 13 patients whose discharge deficit was not known.

 This work was supported by Public Health Services research grant AG15478 from the National Institute on Aging, the Eliot B. and Edith C. Shoolman Fund of Massachusetts General Hospital, and a Hartford Geriatrics Health Outcomes Research Scholars Award from the AGS Foundation for Health in Aging.

PII: S0002-9343(06)01022-9

doi: 10.1016/j.amjmed.2006.07.034

The American Journal of Medicine
Volume 120, Issue 8 , Pages 700-705 , August 2007

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