The American Journal of Medicine
Volume 120, Issue 1 , Pages e1-e3 , January 2007

An Unusual Cause of Lymph Nodes Enlargement

  • Benjamin Terrier, MD

      Affiliations

    • Department of Nephrology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France
  • ,
  • Aurélie Hummel, MD

      Affiliations

    • Department of Nephrology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France
  • ,
  • Aude Servais, MD

      Affiliations

    • Department of Nephrology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France
  • ,
  • Richard Delarue, MD

      Affiliations

    • Department of Hematology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France
  • ,
  • Philippe Fournier, MD

      Affiliations

    • Department of Nephrology, Hôpital Privé de l’Ouest Parisien, Trappes, France
  • ,
  • Fadi Fakhouri, MD

      Affiliations

    • Department of Nephrology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France
    • Corresponding Author InformationRequests for reprints should be addressed to Fadi Fakhouri, MD, Service de Néphrologie Adultes, Hôpital Necker-Enfants Malades, AP-HP, 149-161 rue de Sèvres, 75743 Paris cedex 15, France.

  • Image Result

    Thoracic computed tomography scan, transverse section: Mediastinal mass due to bulky and compressive calcified mediastinal lymph nodes (arrows). Note the presence of axillary subcutaneous calcificatio

    Thoracic computed tomography scan, transverse section: Mediastinal mass due to bulky and compressive calcified mediastinal lymph nodes (arrows). Note the presence of axillary subcutaneous calcifications (arrows).

  • Image Result
    Thoracic computed tomography scan, coronal section: bulky and compressive calcified mediastinal lymph nodes (arrows), and axillary subcutaneous calcification (arrows).

    Thoracic computed tomography scan, coronal section: bulky and compressive calcified mediastinal lymph nodes (arrows), and axillary subcutaneous calcification (arrows).

  • Image Result
    Plain limb x-ray film: presence of widespread subcutaneous calcifications.

    Plain limb x-ray film: presence of widespread subcutaneous calcifications.

  • Image Result
    Cervical lymph node biopsy. Light microscopy. Presence of Congo red positive deposits of AL-amyloidosis in the absence of any granuloma or tumoral cell. Immunofluorescence study shows the exclusive pr

    Cervical lymph node biopsy. Light microscopy. Presence of Congo red positive deposits of AL-amyloidosis in the absence of any granuloma or tumoral cell. Immunofluorescence study shows the exclusive presence of λ light chains in the absence of κ light chains.

PII: S0002-9343(06)00616-4

doi: 10.1016/j.amjmed.2006.04.029

The American Journal of Medicine
Volume 120, Issue 1 , Pages e1-e3 , January 2007