The American Journal of Medicine
Volume 119, Issue 7, Supplement 1 , Pages S30-S35 , July 2006

Incidence and Prevalence of Hyponatremia

  • Ashish Upadhyay, MD

      Affiliations

    • Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
    • Division of Nephrology, Department of Medicine, Caritas St. Elizabeth’s Medical Center, Boston, Massachusetts, USA
    • ,
  • Bertrand L. Jaber, MD

      Affiliations

    • Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
    • Division of Nephrology, Department of Medicine, Caritas St. Elizabeth’s Medical Center, Boston, Massachusetts, USA
    • ,
  • Nicolaos E. Madias, MD

      Affiliations

    • Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
    • Division of Nephrology, Department of Medicine, Caritas St. Elizabeth’s Medical Center, Boston, Massachusetts, USA
    • Corresponding Author InformationRequests for reprints should be addressed to Nicolaos E. Madias, MD, Department of Medicine, Caritas St. Elizabeth’s Medical Center, 736 Cambridge Street, Boston, Massachusetts 02135.

References 

  1. Anderson RJ , Chung H-M , Kluge R , Schrier RW . Hyponatremia (a prospective analysis of its epidemiology and the pathogenetic role of vasopressin) . Ann Intern Med . 1985;102:164–168
  2. Owen JA , Campbell DG . A comparison of plasma electrolyte and urea values in healthy persons and in hospital patients . Clin Chim Acta . 1968;22:611–618
  3. Hawkins RC . Age and gender as risk factors for hyponatremia and hypernatremia . Clin Chim Acta . 2003;337:169–172
  4. Hoorn E , Lindemans J , Zietse R . Hyponatremia in hospitalized patients (epidemiology, etiology and symptomatology) . J Am Soc Nephrol . 2004;15:561A; [abstract]
  5. Chung H-M , Kluge R , Schrier RW , Anderson RJ . Postoperative hyponatremia (a prospective study) . Arch Intern Med . 1986;146:333–336
  6. Baran D , Hutchinson TA . The outcome of hyponatremia in a general hospital population . Clin Nephrol . 1984;22:72–76
  7. DeVita MV , Gardenswartz MH , Konecky A , Zabetakis P . Incidence and etiology of hyponatremia in an intensive care unit . Clin Nephrol . 1990;34:163–166
  8. Bennani SL , Abouqal R , Zeggwagh AA , et al.   Incidence, causes and prognostic factors of hyponatremia in intensive care [in French] . Rev Med Interne . 2003;24:224–229
  9. Lee C-T , Guo H-R , Chen J-B . Hyponatremia in the emergency department . Am J Emerg Med . 2000;18:264–268
  10. Madhusoodanan S , Bogunovic OJ , Moise D , Brenner R , Markowitz S , Sotelo J . Hyponatraemia associated with psychotropic medications (a review of the literature and spontaneous reports) . Adverse Drug React Toxicol Rev . 2002;21:17–29
  11. Wilkinson TJ , Begg EJ , Winter AC , Sainsbury R . Incidence and risk factors for hyponatraemia following treatment with fluoxetine or paroxetine in elderly people . Br J Clin Pharmacol . 1999;47:211–217
  12. Almond CSD , Shin AY , Fortescue EB , et al.   Hyponatremia among runners in the Boston Marathon . N Engl J Med . 2005;352:1550–1556
  13. Miller KK , Grinspoon SK , Ciampa J , Hier J , Herzog D , Klibanski A . Medical findings in outpatients with anorexia nervosa . Arch Intern Med . 2005;165:561–566
  14. Miller M , Morley JE , Rubenstein LZ . Hyponatremia in a nursing home population . J Am Geriatr Soc . 1995;43:1410–1413
  15. Oren RM . Hyponatremia in congestive heart failure . Am J Cardiol . 2005;95(suppl):2B–7B
  16. Lee WH , Packer M . Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure . Circulation . 1986;73:257–267
  17. Binanay C , Califf RM , Hasselblad V , et al.  The ESCAPE Investigators and ESCAPE Study Coordinators   Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness (the ESCAPE trial) . JAMA . 2005;294:1625–1633
  18. Gheorghiade M , Adams K , O’Connor C , et al.   Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes (insights from the acute and chronic therapeutic impact of a vasopressin antagonist in chronic heart failure (ACTIV in CHF) [abstract]) . J Am Coll Cardiol . 2005;45(suppl 1):145A
  19. Porcel A , Diaz F , Rendón P , Macías M , Martín-Herrera L , Girón-González JA . Dilutional hyponatremia in patients with cirrhosis and ascites . Arch Intern Med . 2002;162:323–328
  20. Borroni G , Maggi A , Sangiovanni A , Cazzaniga M , Salerno F . Clinical relevance of hyponatraemia for the hospital outcome of cirrhotic patients . Dig Liver Dis . 2000;32:605–610
  21. Torres JM , Cardenas O , Vasquez A , Schlossberg D . Streptococcus pneumoniae bacteremia in a community hospital . Chest . 1998;113:387–390
  22. Lim WS , Lewis S , Macfarlane JT . Severity prediction rules in community acquired pneumonia (a validation study) . Thorax . 2000;55:219–223
  23. Shann F , Germer S . Hyponatraemia associated with pneumonia or bacterial meningitis . Arch Dis Child . 1985;60:963–966
  24. Singhi S , Dhawan A . Frequency and significance of electrolyte abnormalities in pneumonia . Indian Pediatr . 1992;29:735–740
  25. Tang WW , Kaptein EM , Feinstein EI , Massry SG . Hyponatremia in hospitalized patients with the acquired immunodeficiency syndrome (AIDS) and the AIDS-related complex . Am J Med . 1993;94:169–174
  26. Cusano AJ , Thies HL , Siegal FP , Dreisbach AW , Maesaka JK . Hyponatremia in patients with acquired immune deficiency syndrome . J Acquir Immune Defic Syndr . 1990;3:949–953
  27. Noakes TD , Goodwin N , Rayner BL , Branken T , Taylor RKN . Water intoxication (a possible complication during endurance exercise) . Med Sci Sports Exerc . 1985;17:370–375
  28. Speedy DB , Noakes TD , Rogers IR , et al.   Hyponatremia in ultradistance triathletes . Med Sci Sports Exerc . 1999;31:809–815
  29. Movig KLL , Leufkens HGM , Lenderink AW , Egberts ACG . Validity of hospital discharge International Classification of Diseases (ICD) codes for identifying patients with hyponatremia . J Clin Epidemiol . 2003;56:530–535

PII: S0002-9343(06)00491-8

doi: 10.1016/j.amjmed.2006.05.005

The American Journal of Medicine
Volume 119, Issue 7, Supplement 1 , Pages S30-S35 , July 2006

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