The American Journal of Medicine
Volume 120, Issue 1 , Pages 98.e9-98.e16 , January 2007

Impact of NSAIDS on Mortality and the Effect of Preexisting Coronary Artery Disease in US Veterans

  • Todd A. Lee, PharmD, PhD

      Affiliations

    • Midwest Center for Health Services and Policy Research, Hines Veterans Affairs Hospital, Chicago, Ill
    • Institute for Healthcare Studies and Division of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill
    • Corresponding Author InformationRequests for reprints should be addressed to Todd A. Lee, Midwest Center for Health Services and Policy Research, Hines VA Hospital (151-H), PO Box 5000, Hines, IL 60141.
  • ,
  • Brian Bartle, MPH

      Affiliations

    • Midwest Center for Health Services and Policy Research, Hines Veterans Affairs Hospital, Chicago, Ill
  • ,
  • Kevin B. Weiss, MD, MPH

      Affiliations

    • Midwest Center for Health Services and Policy Research, Hines Veterans Affairs Hospital, Chicago, Ill
    • Institute for Healthcare Studies and Division of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill

  • Image Result

    Study inclusion flow chart for CAD and non-CAD cohorts and number of cases after further inclusion criteria were applied. MI = myocardial infarction; VHA = Veterans Health Administration; CAD = corona

    Study inclusion flow chart for CAD and non-CAD cohorts and number of cases after further inclusion criteria were applied. MI = myocardial infarction; VHA = Veterans Health Administration; CAD = coronary artery disease; NSAID = nonsteroidal anti-inflammatory drug; Rx = prescription; Dx = diagnosis.

  • Image Result
    Risk of all-cause mortality in non-CAD and CAD cohorts by NSAID exposure (lines are 95% confidence interval; non-CAD cohort, solid line; CAD cohort, dashed line). NSAID = nonsteroidal anti-inflammator

    Risk of all-cause mortality in non-CAD and CAD cohorts by NSAID exposure (lines are 95% confidence interval; non-CAD cohort, solid line; CAD cohort, dashed line). NSAID = nonsteroidal anti-inflammatory drug.

 The Midwest Center for Health Services and Policy Research, Hines VA Hospital provided funding. The funding agency had no role in any aspect of the study.The views expressed in this article are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs or of the United States Government.

PII: S0002-9343(06)00270-1

doi: 10.1016/j.amjmed.2006.03.003

The American Journal of Medicine
Volume 120, Issue 1 , Pages 98.e9-98.e16 , January 2007