The American Journal of Medicine
Volume 119, Issue 9 , Pages 768-776 , September 2006

Laryngeal Cancer and Gastroesophageal Reflux Disease: A Case-Control Study

  • Michael F. Vaezi, MD, PhD, MSepi

      Affiliations

    • Department of Gastroenterology, Vanderbilt University Medical Center, Nashville, Tenn
    • Corresponding Author InformationRequests for reprints should be addressed to Michael F. Vaezi, MD, PhD, MSepi, Department of Gastroenterology, Vanderbilt University Medical Center, 1501 TVC, 1301 22nd Ave. South, Nashville, TN 37232-5280.
    • ,
  • Mohammed A. Qadeer, MD

      Affiliations

    • Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio
    • ,
  • Rocio Lopez, MS, MPH

      Affiliations

    • Quantitative Health Sciences, Cleveland Clinic Foundation
    • ,
  • Natalie Colabianchi, PhD

      Affiliations

    • Department of Epidemiology, Case Western Reserve University, Cleveland, Ohio

  • Image Result

    Flowchart depicting the process of patient selection.

    Flowchart depicting the process of patient selection.

  • Image Result

    Smoking duration and risk of developing laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

    Smoking duration and risk of developing laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

  • Image Result

    Smoking intensity and risk of laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

    Smoking intensity and risk of laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

  • Image Result

    Relationship between duration and intensity of smoking and laryngeal cancer development. OR=odds ratio; ppd=packs per day.

    Relationship between duration and intensity of smoking and laryngeal cancer development. OR=odds ratio; ppd=packs per day.

  • Image Result

    Smoking cessation and the likelihood of developing laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

    Smoking cessation and the likelihood of developing laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

  • Image Result

    Alcohol intake (drinks per day) and risk of laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

    Alcohol intake (drinks per day) and risk of laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval.

  • Image Result

    Estimated probability of laryngeal cancer based on tobacco consumption and GERD status. GERD=gastroesophageal reflux disease.

    Estimated probability of laryngeal cancer based on tobacco consumption and GERD status. GERD=gastroesophageal reflux disease.

PII: S0002-9343(06)00159-8

doi: 10.1016/j.amjmed.2006.01.019

The American Journal of Medicine
Volume 119, Issue 9 , Pages 768-776 , September 2006

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