The American Journal of Medicine
Volume 120, Issue 1 , Pages 47-53 , January 2007

Trend in Mortality after Stroke with Atrial Fibrillation

  • Lars Frost, MD, PhD

      Affiliations

    • Department of Cardiology A, Aarhus University Hospital, Aarhus, Denmark
    • Corresponding Author InformationReprint requests should be addressed to Lars Frost, MD, PhD, Department of Cardiology A, Aarhus University Hospital, Tage Hansens Gade, DK-8000 Aarhus C, Denmark.
    • ,
  • Ljubica Vukelic Andersen, MD

      Affiliations

    • Department of Cardiology A, Aarhus University Hospital, Aarhus, Denmark
    • ,
  • Peter Vestergaard, MD, PhD, DMSc

      Affiliations

    • Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark
    • ,
  • Steen Husted, MD, DMSc

      Affiliations

    • Department of Cardiology A, Aarhus University Hospital, Aarhus, Denmark
    • ,
  • Leif Spange Mortensen, MSc

      Affiliations

    • UNI-C, The Danish Information Technology Centre for Education and Research, Aarhus, Denmark.

References 

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  2. Feigin VL, Lawes CM, Bennett DA, Anderson CS. Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century. Lancet Neurol. 2003;2:43–53
  3. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major contributor to stroke in the elderly (The Framingham Study). Arch Intern Med. 1987;147:1561–1564
  4. Lin HJ, Wolf PA, Kelly-Hayes M, et al. Stroke severity in atrial fibrillation (The Framingham Study). Stroke. 1996;27:1760–1764
  5. Dulli DA, Stanko H, Levine RL. Atrial fibrillation is associated with severe acute ischemic stroke. Neuroepidemiology. 2003;22:118–123
  6. Marini C, De Santis F, Sacco S, et al. Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke. 2005;36:1115–1119
  7. Miyasaka Y, Barnes ME, Gersh BJ, et al. Time trends of ischemic stroke incidence and mortality in patients diagnosed with first atrial fibrillation in 1980 to 2000: report of a community-based study. Stroke. 2005;36:2362–2366
  8. Andersen TF, Madsen M, Jorgensen J, Mellemkjoer L, Olsen JH. The Danish National Hospital Register (A valuable source of data for modern health sciences). Dan Med Bull. 1999;46:263–268
  9. National Institute of Neurological Disorders and Stroke Ad Hoc Committee. Special report from the National Institute of Neurological Disorders and Stroke (Classification of cerebrovascular diseases: III). Stroke. 1990;21:637–676
  10. Greenland S. Modeling and variable selection in epidemiologic analysis. Am J Public Health. 1989;79:340–349
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  12. Rothwell PM, Coull AJ, Giles MF, et al. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet. 2004;363:1925–1933
  13. Frost L, Vestergaard P, Mosekilde L, Mortensen LS. Trends in incidence and mortality in the hospital diagnosis of atrial fibrillation or flutter in Denmark, 1980-1999. Int J Cardiol. 2005;103:78–84
  14. Frost L, Johnsen SP, Pedersen L, Toft E, Husted S, Sorensen HT. Atrial fibrillation or flutter and stroke: a Danish population-based study of the effectiveness of oral anticoagulation in clinical practice. J Intern Med. 2002;252:64–69
  15. Friberg J, Gislason GH, Gadsboll N, et al. Temporal trends in the prescription of vitamin K antagonists in patients with atrial fibrillation. J Intern Med. 2006;259:173–178
  16. Hylek EM, Go AS, Chang Y, et al. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med. 2003;349:1019–1026
  17. EAFT (European Atrial Fibrillation Trial) Study Group. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. Lancet. 1993;342:1255–1262
  18. Nielsen HW, Tuchsen F, Jensen MV. [Validity of the diagnosis “essential hypertension” in the National Patient Registry]. Ugeskr Laeger. 1996;158:163–167
  19. Frost L, Vestergaard P. Alcohol and risk of atrial fibrillation or flutter: a cohort study. Arch Intern Med. 2004;164:1993–1998
  20. Petersen P, Boysen G, Godtfredsen J, Andersen ED, Andersen B. Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation (The Copenhagen AFASAK study). Lancet. 1989;1:175–179
  21. The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation (The Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators). N Engl J Med. 1990;323:1505–1511
  22. Stroke Prevention in Atrial Fibrillation Study (Final results). Circulation. 1991;84:527–539
  23. Connolly SJ, Laupacis A, Gent M, Roberts RS, Cairns JA, Joyner C. Canadian Atrial Fibrillation Anticoagulation (CAFA) Study. J Am Coll Cardiol. 1991;18:349–355
  24. Ezekowitz MD, Bridgers SL, James KE, et al. Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation (Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigators). N Engl J Med. 1992;327:1406–1412
  25. Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II Study. Lancet. 1994;343:687–691

PII: S0002-9343(06)00095-7

doi: 10.1016/j.amjmed.2005.12.027

The American Journal of Medicine
Volume 120, Issue 1 , Pages 47-53 , January 2007

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