The American Journal of Medicine
Volume 119, Issue 4, Supplement 1 , Pages S12-S17 , April 2006

Persistence with Bisphosphonate Treatment for Osteoporosis: Finding the Root of the Problem

  • Joyce A. Cramer, BS

      Affiliations

    • Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    • Corresponding Author InformationRequests for reprints should be addressed to Joyce A. Cramer, BS, Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue (G7E), West Haven, Connecticut 06516-2770.
  • ,
  • Stuart Silverman, MD

      Affiliations

    • Departments of Rheumatology and Medicine, Cedars-Sinai Hospital, University of California, Los Angeles, California, USA

  • Image Result

    Compliance influences change in bone mineral density (BMD) in patients treated with bisphosphonates. (Adapted with permission from Osteoporos Int.16)

    Compliance influences change in bone mineral density (BMD) in patients treated with bisphosphonates. (Adapted with permission from Osteoporos Int.16)

  • Image Result

    (A) Medication persistence: percentage of persistent patients on daily and weekly bisphosphonates as a function of time. (B) Mean medication possession ratios (± confidence interval) for daily and wee

    (A) Medication persistence: percentage of persistent patients on daily and weekly bisphosphonates as a function of time. (B) Mean medication possession ratios (± confidence interval) for daily and weekly bisphosphonate cohorts. *P = 0.0001; P = 0.002. (Reprinted with permission from Curr Med Res Opin.28)

PII: S0002-9343(05)01198-8

doi: 10.1016/j.amjmed.2005.12.018

The American Journal of Medicine
Volume 119, Issue 4, Supplement 1 , Pages S12-S17 , April 2006