The American Journal of Medicine
Volume 119, Issue 3 , Pages 203-216 , March 2006

Multidetector Computed Tomography for the Diagnosis of Coronary Artery Disease: A Systematic Review

  • Paul D. Stein, MD

      Affiliations

    • Department of Research, St. Joseph Mercy Oakland Hospital, Pontiac, Mich.
    • Department of Internal Medicine, Wayne State University, Detroit, Mich.
    • Corresponding Author InformationRequests for reprints should be addressed to Paul D. Stein, MD, Saint Joseph Mercy Oakland, 44405 Woodward Avenue, Pontiac, MI 48341-2985.
  • ,
  • Afzal Beemath, MD

      Affiliations

    • Department of Research, St. Joseph Mercy Oakland Hospital, Pontiac, Mich.
  • ,
  • Fadi Kayali, MD

      Affiliations

    • Department of Research, St. Joseph Mercy Oakland Hospital, Pontiac, Mich.
  • ,
  • Elias Skaf, MD

      Affiliations

    • Department of Research, St. Joseph Mercy Oakland Hospital, Pontiac, Mich.
  • ,
  • Julia Sanchez, MD

      Affiliations

    • Department of Research, St. Joseph Mercy Oakland Hospital, Pontiac, Mich.
  • ,
  • Ronald E. Olson, PhD

      Affiliations

    • Office of Grants, Contracts and Sponsored Research, Oakland University, Rochester, Mich.

,Revised 30 June 2005 ,Accepted 30 June 2005.

References 

  1. Dowe DA. The current status and future of coronary CT Angiography. Consultations in computed tomography. Available at: www.mhsource.com/mrp. Accessed December 9, 2004
  2. Achenbach S , Daniel WG . Noninvasive coronary angiography-an acceptable alternative? . N Engl J Med . 2001;345:1909–1910
  3. Kennedy RH , Kennedy MA , Frye RL , et al.   Cardiac-catheterization and cardiac-surgical facilities (use, trends, and future requirements) . N Engl J Med . 1982;307:986–993
  4. Johnson LW , Lozner EC , Johnson S , et al.   Coronary arteriography 1984-1987: a report of the Registry of the Society for Cardiac Angiography and Interventions. I. Results and complications . Cathet Cardiovasc Diagn . 1989;17:5–10
  5. AHA Hospital Statistics, 2006 Edition . Chicago: American Hospital Association; 2006; xiv,6,158,161
  6. Bossuyt PM , Reitsma JB , Bruns DE , et al.   The STARD statement for reporting studies of diagnostic accuracy (explanation and elaboration) . Ann Intern Med . 2003;138:W1–W12
  7. Lijmer JG , Mol BW , Heisterkamp S , et al.   Empirical evidence of design-related bias in studies of diagnostic tests . J Am Med Assoc . 1999;282:1061–1066
  8. Cook DJ , Mulrow CD , Haynes RB . Systematic reviews (synthesis of best evidence for clinical decisions) . Ann Intern Med . 1997;126:376–380
  9. Austen WG , Edwards JE , Frye RL , et al.   A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association . Circulation . 1975;51:5–40
  10. Gaudio C , Mirabelli F , Alessandra BL , et al.   Noninvasive assessment of coronary artery stenoses by multidetector-row spiral computed tomography; comparison with conventional angiography . Eur Rev Med Pharm Sci . 2005;9:13–21
  11. Leber AW , Knez A , Becker C , et al.   Non-invasive intravenous coronary angiography using electron beam tomography and multislice computed tomography . Heart . 2003;89:633–639
  12. Nieman K , Rensing BJ , van Geuns RJ , et al.   Usefulness of multislice computed tomography for detecting obstructive coronary artery disease . Am J Cardiol . 2002;89:913–918
  13. Nieman K , Oudkerk M , Rensing BJ , et al.   Coronary angiography with multi-slice computed tomography . Lancet . 2001;357:599–603
  14. Sato Y , Matsumoto N , Kato M , et al.   Noninvasive assessment of coronary artery disease by multislice spiral computed tomography using a new retrospectively ECG-gated image reconstruction technique . Circ J . 2003;67:401–405
  15. Dirksen MS , Jukema JW , Bax JJ , et al.   Cardiac multidetector-row computed tomography in patients with unstable angina . Am J Cardiol . 2005;95:457–461
  16. Becker CR , Knez A , Leber A , et al.   Detection of coronary artery stenoses with multislice helical CT angiography . J Comput Assist Tomogr . 2002;26:750–755
  17. Herzog C , Ay M , Engelmann K , et al.   Visualization techniques in multislice CT-coronary angiography of the heart. Correlations of axial, multiplanar, three-dimensional and virtual endoscopic imaging with the invasive diagnosis . Rofo . 2001;173:341–349
  18. Giesler T , Baum U , Ropers D , et al.   Noninvasive visualization of coronary arteries using contrast-enhanced multidetector CT (influence of heart rate on image quality and stenosis detection) . Am J Roentgenol . 2002;179:911–916
  19. Kopp AF , Schroeder S , Kuettner A , et al.   Non-invasive coronary angiography with high resolution multidetector-row computed tomography. Results in 102 patients . Eur Heart J . 2002;23:1714–1725
  20. Morgan-Hughes GJ , Marshall AJ , Roobottom CA . Multislice computed tomographic coronary angiography (experience in a UK centre) . Clin Radiol . 2003;58:378–383
  21. Maruyama T , Yoshizumi T , Tamura R , et al.   Comparison of visibility and diagnostic capability of noninvasive coronary angiography by eight-slice multidetector-row computed tomography versus conventional coronary angiography . Am J Cardiol . 2004;93:537–542
  22. Matsuo S , Nakamura Y , Matsumoto T , et al.   Visual assessment of coronary artery stenosis with electrocardiographically-gated multislice computed tomography . Int J Cardiovasc Imaging . 2004;20:67–69
  23. Hoffmann MHK , Shi H , Schmitz BL , et al.   Noninvasive coronary angiography with multislice computed tomography . J Am Med Assoc . 2005;293:2471–2478
  24. Hoffmann U , Moselewski F , Cury RC , et al.   Predictive value of 16-slice multidetector spiral computed tomography to detect significant obstructive coronary artery disease in patients at high risk for coronary artery disease (patient-versus segment-based analysis) . Circulation . 2004;110:2638–2643
  25. Nieman K , Cademartiri F , Lemos PA , Raaijmakers R , Pattynama PM , de Feyter PJ . Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography . Circulation . 2002;106:2051–2054
  26. Kuettner A , Beck T , Drosch T , et al.   Diagnostic accuracy of noninvasive coronary imaging using 16-detector slice spiral computed tomography with 188 ms temporal resolution . J Am Coll Cardiol . 2005;45:123–127
  27. Martuscelli E , Romagnoli A , D’Eliseo A , et al.   Accuracy of thin-slice computed tomography in the detection of coronary stenoses . Eur Heart J . 2004;25:1043–1048
  28. Ropers D , Baum U , Pohle K , et al.   Detection of coronary artery stenoses with thin-slice multi-detector row spiral computed tomography and multiplanar reconstruction . Circulation . 2003;107:664–666
  29. Zhang ZH , Jin ZY , Li DJ , et al.   Non-invasive imaging of coronary artery with 16-slice spiral computed tomography . Chin Med Sci J . 2004;19:174–179
  30. Cademartiri F , Runza G , Marano R , et al.   Diagnostic accuracy of 16-row multislice CT angiography in the evaluation of coronary segments . Radiol Med . 2005;109:91–97 (Torino)
  31. Moon JY , Chung N , Choi BW , et al.   The utility of multi-detector row spiral CT for detection of coronary artery stenoses . Yonsei Med J . 2005;46:86–94
  32. Paul JF , Ohanessian A , Caussin C , et al.   Visualization of coronary tree and detection of coronary artery stenosis using 16-slice, sub-millimeter computed tomography (preliminary experience) . Arch Mal Coeur Vaiss . 2004;97:31–36
  33. Schuijf JD , Bax JJ , Salm LP , et al.   Noninvasive coronary imaging and assessment of left ventricular function using 16-slice computed tomography . Am J Cardiol . 2005;95:571–574
  34. Mollet NR , Cademartiri F , Krestin GP , et al.   Improved diagnostic accuracy with 16-row multi-slice computed tomography coronary angiography . J Am Coll Cardiol . 2005;45:128–132
  35. Mollet NR , Cademartiri F , Nieman K , et al.   Multislice spiral computed tomography coronary angiography in patients with stable angina pectoris . J Am Coll Cardiol . 2004;43:2265–2270
  36. Kuettner A , Trabold T , Schroeder S , et al.   Noninvasive detection of coronary lesions using 16-detector multislice spiral computed tomography technology (initial clinical results) . J Am Coll Cardiol . 2004;44:1230–1237
  37. Leta R , Carreras F , Alomar X , et al.   Non-invasive coronary angiography with 16 multidetector-row spiral computed tomography (a comparative study with invasive coronary angiography) . Rev Esp Cardiol . 2004;57:217–224
  38. Martuscelli E , Razzini C , D’Eliseo A , Marchei M , Pisani E , Romeo F . Limitations of four-slice multirow detector computed tomography in the detection of coronary stenosis . Ital Heart J . 2004;5:127–131
  39. Achenbach S , Giesler T , Ropers D , et al.   Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography . Circulation . 2001;103:2535–2538
  40. Knez A , Becker CR , Leber A , et al.   Usefulness of multislice spiral computed tomography angiography for determination of coronary artery stenoses . Am J Cardiol . 2001;88:1191–1194
  41. Mennicke M , Giesler T , Ropers D , et al.   Influence of heart rate on image quality and detection of coronary stenoses with multislice spiral CT . Biomed Tech . 2002;47(Suppl 1):782–785 (Berl)
  42. Leschka S , Alkadhi H , Plass A , et al.   Accuracy of MSCT coronary angiography with 64-slice technology (first experience) . Eur Heart J . 2005;26:1482–1487
  43. Jaeschke R , Guyatt GH , Sackett DL  The Evidence-Based Medicine Working Group . Users’ guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? . J Am Med Assoc . 1994;271:703–707
  44. Herzog C , Abolmaali N , Balzer JO , et al.   Heart-rate-adapted image reconstruction in multidetector-row cardiac CT (influence of physiological and technical prerequisite on image quality) . Eur Radiol . 2002;12:2670–2678
  45. Becker CR , Knez A , Ohnesorge B , Schoepf UJ , Reiser MF . Imaging of noncalcified coronary plaques using helical CT with retrospective ECG gating . AJR Am J Roentgenol . 2000;175:423–424
  46. Kopp AF , Schroeder S , Baumbach A , et al.   Non-invasive characterization of coronary lesion morphology and composition by multislice CT (first results in comparison with intracoronary ultrasound) . Eur Radiol . 2001;11:1607–1611
  47. Schroeder S , Kopp AF , Baumbach A , et al.   Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography . J Am Coll Cardiol . 2001;37:1430–1435
  48. Achenbach S , Daniel WG . Imaging of coronary atherosclerosis using computed tomography (current status and future directions) . Curr Atheroscler Rep . 2004;6:213–218
  49. De Feyter PJ , Nieman K . Noninvasive multi-slice computed tomography coronary angiography. An emerging clinical modality . J Am Coll Cardiol . 2004;44:1238–1240
  50. Agency for Healthcare Research and Quality, Healthcare Cost and Utilization Project, HCUPnet, www.ahrq.gov/data/hcup. Accessed January 19, 2006.
  51. Garcia MJ . Noninvasive coronary angiography. Hype or new paradigm? . J Am Med Assoc . 2005;293:2531–2533
  52. Schroeder S , Kopp AF , Kuettner A , et al.   Influence of heart rate on vessel visibility in noninvasive coronary angiography using new multislice computed tomography (experience in 94 patients) . Clin Imaging . 2002;26:106–111
  53. Application Guide . Forchheim: Siemens AG Medical Solutions; 2004;
  54. Hunold P , Vogt FM , Schmermund A , et al.   Radiation exposure during cardiac CT (effective doses at multi-detector row CT and electron-beam CT) . Radiology . 2003;226:145–152
  55. Annals of the International Commission of Radiological Protection (ICRP). Available at: http://www.icrp.org/docs/Summary_B-scan_ICRP_60_Ann_ICRP_1990_Recs.pdf. Accessed January 18, 2006.
  56. Crean A , Dutka D , Coulden R . Cardiac imaging using nuclear medicine and positron emission tomography . Radiol Clin North Am . 2004;42:619–634
  57. Tardif JC , Vannan MA , Taylor K , Schwartz SL , Pandian NG . Delineation of extended lengths of coronary arteries by multiplane transesophageal echocardiography . J Am Coll Cardiol . 1994;24:909–919
  58. Caiati C , Montaldo C , Zedda N , Bina A , Iliceto S . New noninvasive method for coronary flow reserve assessment (contrast-enhanced transthoracic second harmonic echo Doppler) . Circulation . 1999;99:771–778
  59. Dix WR , Kupper W , Dill T , et al.   Comparison of intravenous coronary angiography using synchrotron radiation with selective coronary angiography . J Synchrotron Radiat . 2003;10:219–227
  60. Achenbach S , Moshage W , Ropers D , Nossen J , Daniel WG . Value of electron-beam computed tomography for the noninvasive detection of high-grade coronary-artery stenoses and occlusions . N Engl J Med . 1998;339:1964–1971
  61. Schmermund A , Rensing BJ , Sheedy PF , Bell MR , Rumberger JA . Intravenous electron-beam computed tomographic coronary angiography for segmental analysis of coronary artery stenoses . J Am Coll Cardiol . 1998;31:1547–1554
  62. Budoff MJ , Oudiz RJ , Zalace CP , et al.   Intravenous three-dimensional coronary angiography using contrast enhanced electron beam computed tomography . Am J Cardiol . 1999;83:840–845
  63. Manning WJ , Li W , Edelman RR . A preliminary report comparing magnetic resonance coronary angiography with conventional angiography . N Engl J Med . 1993;328:828–832
  64. Stuber M , Botnar RM , Kissinger KV , Manning WJ . Free-breathing black-blood coronary MR angiography (initial results) . Radiology . 2001;219:278–283
  65. Regenfus M , Ropers D , Achenbach S , et al.   Noninvasive detection of coronary artery stenosis using contrast-enhanced three-dimensional breath-hold magnetic resonance coronary angiography . J Am Coll Cardiol . 2000;36:44–50
  66. van Geuns RJ , Wielopolski PA , de Bruin HG , et al.   MR coronary angiography with breath-hold targeted volumes (preliminary clinical results) . Radiology . 2000;217:270–277
  67. Ikonen AE , Manninen HI , Vainio P , et al.   Three-dimensional respiratory-gated coronary MR angiography with reference to X-ray coronary angiography . Acta Radiol . 2003;44:583–589
  68. Kim WY , Danias PG , Stuber M , et al.   Coronary magnetic resonance angiography for the detection of coronary stenoses . N Engl J Med . 2001;345:1863–1869
  69. Kaandorp TAM , Lamb HJ , Bax JJ , van der Wall EE , de Roos A . Magnetic resonance imaging of coronary arteries, the ischemic cascade, and myocardial infarction . Am Heart J . 2005;149:200–208
  70. White RD , Breen JF . Current and future clinical applications of contrast-enhanced cardiac CT (the clinics’ perspective) . Int J Cardiovasc Imaging . 2001;17:477–478
  71. Achenbach S , Hoffmann U , Ferencik M , Wicky S , Brady TJ . Tomographic coronary angiography by EBCT and MDCT . Prog Cardiovasc Dis . 2003;46:185–195
  72. Kondos GT , Hoff JA , Sevrukov A , et al.   Electron-beam tomography coronary artery calcium and cardiac events (a 37-month follow-up of 5635 initially asymptomatic low- to intermediate-risk adults) . Circulation . 2003;107:2571–2576
  73. Shaw LJ , Raggi P , Schisterman E , Berman DS , Callister TQ . Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortality . Radiology . 2003;228:826–833

PII: S0002-9343(05)00657-1

doi: 10.1016/j.amjmed.2005.06.071

The American Journal of Medicine
Volume 119, Issue 3 , Pages 203-216 , March 2006