The American Journal of Medicine
Volume 118, Issue 12 , Pages 1414.e1-1414.e5 , December 2005

Lipid levels and bone mineral density

  • Daniel H. Solomon, MD, MPH

      Affiliations

    • Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass
    • Division of Rheumatology, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass
    • Dr. Solomon receives salary support from NIH AR-48616, the Arthritis Foundation, and the Engalitcheff Arthritis Outcomes Initiative.
    • Corresponding Author InformationRequests for reprints should be addressed to Daniel H. Solomon, MD, MPH, Division of Pharmacoepidemiology, Brigham and Women’s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120
    • ,
  • Jerry Avorn, MD

      Affiliations

    • Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass
    • ,
  • Claire F. Canning, MA

      Affiliations

    • Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass
    • ,
  • Philip S. Wang, MD, DrPH

      Affiliations

    • Division of Pharmacoepidemiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass
    • Department of Psychiatry, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass

References 

  1. Hofbauer LC , Schoppet M . Clinical implications of the osteoprotegrin/RANKL/ RANK system for bone and vascular diseases . JAMA . 2004;292:490–495
  2. Samelson EJ , Kiel DP , Broe KE , et al.   Metacarpal cortical area and risk of coronary heart disease (the Framingham Study) . Am J Epidemiol . 2004;159:589–595
  3. Varosy PD , Shlipak  , Vittinghoff E , et al.   Fracture and risk of coronary events in women with heart disease . Am J Med . 2003;115:196–202
  4. Mundy G , Garrett R , Harris S , et al.   Stimulation of bone formation in vitro and in rodents by statins . Science . 1999;286:1946–1949
  5. Wang PS , Solomon DH , Mogun H , Avorn J . HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients . JAMA . 2000;283:3211–3216
  6. Chan KA , Andrade SE , Boles M , et al.   Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women . Lancet . 2000;355:2185–2188
  7. Meier CR , Schlienger RG , Kraenzlin ME , Schlegel B , Jick H . HMG-CoA reductase inhibitors and the risk of fractures . JAMA . 2000;283:3205–3210
  8. Edwards CJ , Hart DJ , Spector TD . Oral statins and increased bone-mineral density in postmenopausal women . Lancet . 2000;355:2218–2219
  9. Schoofs MW , Sturkeboom MC , van der Klift M , Hofman A , Pols HA , Stricker BH . HMG-coA reductase inhibitors and the risk of vertebral fractures . J Bone Miner Res . 2004;19:1525–1530
  10. Reid IR , Hague W , Emberson J , et al.   Effect of pravastatin on frequency of fracture in the LIPID study (secondary analysis of a randomised controlled trial) . Lancet . 2001;357:509–512
  11. Heart Protection Study Collaborative Group . MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals (a randomised placebo-controlled trial) . Lancet . 2002;360:23–33
  12. Rothman KJ , Greenland S . Modern Epidemiology . 2nd edition.. Philadelphia, Pennsylvania: Lippincott Williams and Wilkins; 1998;
  13. Adami S , Braga V , Zamboni M , et al.   Relationship between lipids and bone mass in 2 cohorts of healthy women and men . Osteoporos Int . 2004;74:136–142
  14. Wahner HW , Looker A , Dunn WL , Walters LC , Hauser MF , Novak C . Quality control of bone densitometry in a national health survey (NHANES III) using three mobile examination centers . J Bone Miner Res . 1994;9:951–960
  15. Johnson CL , Rifkind BM , Sempos CT , et al.   Declining serum total cholesterol levels among US adults (the National Health and Nutrition Examination Surveys) . JAMA . 1993;269:3002–3008
  16. Nesby-O’Dell S , Scanlon KS , Cogswell ME , et al.   Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age (third National Health and Nutrition Examination Survey, 1988–1994) . Am J Clin Nutr . 2002;76:187–192
  17. Gunter EW, Lewis BG, Koncikowski SM. Laboratory procedures used for the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994. Available at: http://www.cdc.gov/nchs/data/nhanes/nhanes3/cdrom/nchs/manuals/labman.pdf. Accessed October 3, 2005.
  18. Spector WD . Functional disability scales . In:  Spilker B editors. Quality of Life Assessment for Clinical Trials . New York, New York: Raven Press; 1990;
  19. Nelson KM , Reiber PG , Boyko MEJ . Diet and exercise among adults with type 2 diabetes . Diabetes Care . 2002;25:1722–1728

PII: S0002-9343(05)00625-X

doi: 10.1016/j.amjmed.2005.07.031

The American Journal of Medicine
Volume 118, Issue 12 , Pages 1414.e1-1414.e5 , December 2005

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