The American Journal of Medicine
Volume 118, Issue 12 , Pages 1413.e15-1413.e22 , December 2005

Hepatitis B virus infection: Current status

  • Ponsiano Ocama, MD

      Affiliations

    • Mulago Hospital, Kampala, Uganda
  • ,
  • Christopher K. Opio, MD

      Affiliations

    • Mulago Hospital, Kampala, Uganda
  • ,
  • William M. Lee, MD

      Affiliations

    • University of Texas Southwestern Medical School, Division of Digestive and Liver Diseases, Dallas, Tex
    • William M. Lee, MD, receives research support from Schering, Roche, Bristol Myers Squibb, Gilead, and Glaxo SmithKline.
    • Corresponding Author InformationRequests for reprints should be addressed to William M. Lee, MD, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390-9151

Received 24 May 2005 ,Revised 15 June 2005 ,Accepted 15 June 2005.

References 

  1. Mast EE , Mahoney FJ , Alter MJ , Margolis HS . Progress toward elimination of Hepatitis B transmission in the United States . Vaccine . 1998;16(Suppl):S48–S51
  2. McQuillan GM , Coleman PJ , Kruszon-Moran D , Moyer LA , Lambert SB , Margolis HS . Prevalence of hepatitis B virus infection in the United States (the National Health and Nutrition Examination Surveys, 1976 through 1994) . Am J Public Health . 1999;89:14–18
  3. Seeger C , Mason WS . Hepatitis B virus biology . Microbiol Mol Biol Rev . 2000;64:51–68
  4. Hunt CM , McGill JM , Allen MI , Condreay LD . Clinical relevance of hepatitis B virus mutations . Hepatology . 2000;31:1037–1044
  5. Chisari FV , Ferrari C . Hepatitis B virus immunopathogenesis . Ann Rev Immunol . 1995;13:29–60
  6. Hadziyannis SJ , Vassilopoulos D . Hepatitis B e antigen-negative chronic hepatitis B . Hepatology . 2001;34:617–624
  7. Ljunggren KK , Miyakawa Y , Kidd AH . Genetic variability in hepatitis B viruses . J Gen Virol . 2002;83;:1267–1280
  8. Fung SK , Lok AS . Hepatitis B genotypes (do they play a role in the outcome of HBV infection?) . Hepatology . 2004;40:790–792
  9. Davies SE , Portmann BC , O’Grady JG , Aldis PM , Chaggar K , Alexander GJ , et al.   Hepatic histological findings after transplantation for chronic hepatitis B virus infection, including a unique pattern of fibrosing cholestatic hepatitis . Hepatology . 1991;13:150–157
  10. Yeo W , Chan PKS , Zhong S , Ho WM , Steinberg JL , Tam JS , et al.   Frequency of hepatitis B virus reactivation in cancer patients undergoing cytotoxic chemotherapy (a prospective study of 626 patients with identification of risk factors) . J Med Virol . 2000;62:299–307
  11. Chu CJ , Hussain M , Lok ASF . Quantitative serum HBV DNA levels during different stages of chronic hepatitis B infection . Hepatology . 2002;36:1408–1415
  12. Hadziyannis SJ , Vassilopoulos D . Hepatitis B e antigen-negative chronic hepatitis B . Hepatology . 2001;34:617–624
  13. Brook MG , Karayiannis P , Thomas HC . Which patients with chronic hepatitis B virus infection will respond to alfa-interferon therapy? A statistical analysis of predictive factors . Hepatology . 1989;10:761–763
  14. Marcellin P , Lau GK , Bonino F , Farci P , Hadziyannis S , Jin R , et al.   Peginterferon alfa-2a alone, lamivudine alone, and the two in combination inpatients with HBeAg-negative chronic hepatitis B . N Engl J Med . 2004;351:1206–1217
  15. Lai CL , Chien RN , Leung NWY , Chang TT , Guan R , Tai DI , et al.   A one year trial of lamivudine for chronic hepatitis B . N Engl J Med . 1998;339:61–68
  16. Perrillo RP , Wright T , Rakela J , Levy G , Schiff E , Gish R , et al.   A multi-center United States-Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B . Hepatology . 2001;33:424–443
  17. Marcellin P , Chang TT , Lim SG , Tong MJ , Sievert W , Shiffman ML , et al.   Adefovir dipivoxil for the treatment of patients with hepatitis B e antigen-positive chronic hepatitis B . N Engl J Med . 2003;348:808–816
  18. Lai CL , Rosmawati M , Lao J , Vlierberghe HV , Anderson FH , Thomas N , et al.   Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection . Gastroenterology . 2002;123:1831–1838
  19. Liaw YF , Leung N , Guan R , Lau GK , Merican I  Asian-Pacific Consensus Working Parties on Hepatitis B . Asian-Pacific consensus statement on the management of chronic hepatitis B (an update) . J Gastroenterol Hepatol . 2003;18:239–245
  20. Franchis R , Hadengue A , Lau GK , Lavanchy D , Lok A , McIntyre N , et al.  EASL Jury   EASL International Consensus Conference on Hepatitis B . J Hepatol . 2003;39(Supp1):S3–S25
  21. Lok AS , McMahon BJ . Chronic hepatitis B (Update of recommendations) . Hepatology . 2004;39:857–861
  22. Keeffe EB , Dieterich DT , Schiff ER , Tobias H , Han SH , Wright TL , et al.   A treatment algorithm for the management of chronic hepatitis B virus infection in the United States . Clin Gastroenterol Hepatol . 2004;2:87–106

PII: S0002-9343(05)00477-8

doi: 10.1016/j.amjmed.2005.06.021

The American Journal of Medicine
Volume 118, Issue 12 , Pages 1413.e15-1413.e22 , December 2005