The American Journal of Medicine
Volume 118, Issue 3 , Pages 212-216, March 2005

Toxoplasmosis in pregnancy

  • Jeffrey D. Kravetz, MD

      Affiliations

    • Yale University School of Medicine, New Haven, Connecticut, and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut
    • Corresponding Author InformationRequests for reprints should be addressed to Jeffrey D. Kravetz, MD, 950 Campbell Avenue, 11ACSL, West Haven, Connecticut 06516
  • ,
  • Daniel G. Federman, MD

      Affiliations

    • Yale University School of Medicine, New Haven, Connecticut, and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut

Received 18 March 2004; accepted 10 August 2004.

Abstract 

Pregnant women who acquire infection from Toxoplasma gondii usually remain asymptomatic, although they can still transmit the infection to their fetuses with severe consequences. Given the asymptomatic nature of most Toxoplasma infections, primary prevention in pregnant women may lower the risk of congenital toxoplasmosis. Both consumption of undercooked meat and unprotected contact with soil are independent risk factors for T. gondii seroconversion during pregnancy, while contact with cat litter may pose a risk in certain situations. However, many pregnant women lack knowledge of these risk factors. This article reviews toxoplasmosis infection in pregnancy, with an emphasis on risk factors and appropriate counseling of pregnant women.

Keywords:  Toxoplasmosis , Congenital infection , Primary prevention , Risk factors

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PII: S0002-9343(04)00700-4

doi:10.1016/j.amjmed.2004.08.023

The American Journal of Medicine
Volume 118, Issue 3 , Pages 212-216, March 2005