The American Journal of Medicine
Volume 117, Issue 9 , Pages 643-649 , 1 November 2004

Effectiveness of glucosamine for symptoms of knee osteoarthritis: Results from an internet-based randomized double-blind controlled trial

  • Timothy McAlindon, MD, MPH

      Affiliations

    • Division of Rheumatology (TM, MF), Tufts–New England Medical Center, Boston, Massachusetts
    • Corresponding Author InformationRequests for reprints should be addressed to Timothy McAlindon, MD, MPH, Division of Rheumatology, Tufts–New England Medical Center, Box 406, 750 Washington Street, Boston, Massachusetts 02111
    • ,
  • Margaret Formica, MSPH

      Affiliations

    • Division of Rheumatology (TM, MF), Tufts–New England Medical Center, Boston, Massachusetts
    • ,
  • Michael LaValley, PhD

      Affiliations

    • Clinical Epidemiology Research and Training Unit (ML, ML, KK), Boston University School of Medicine, Boston, Massachusetts
    • ,
  • Melissa Lehmer, MPH

      Affiliations

    • Clinical Epidemiology Research and Training Unit (ML, ML, KK), Boston University School of Medicine, Boston, Massachusetts
    • ,
  • Karim Kabbara, MCIS

      Affiliations

    • Clinical Epidemiology Research and Training Unit (ML, ML, KK), Boston University School of Medicine, Boston, Massachusetts

Received 15 August 2003 ,Accepted 10 June 2004.

  • Image Result

    Flow diagram of participant progress through phases of the trial. The asterisk (*) indicates prior to week 6. The dagger (†) indicates inclusion of subjects who participated at least through week 6.

    Flow diagram of participant progress through phases of the trial. The asterisk (*) indicates prior to week 6. The dagger (†) indicates inclusion of subjects who participated at least through week 6.

  • Image Result

    Mean pain scores and 95% confidence intervals at online assessment time points throughout the trial. Higher scores indicate more pain. Pain scores did not differ by treatment group at any online asses

    Mean pain scores and 95% confidence intervals at online assessment time points throughout the trial. Higher scores indicate more pain. Pain scores did not differ by treatment group at any online assessment or in intent-to-treat analyses.

 This study was supported by a grant from the Arthritis Foundation and through support from the National Library of Medicine (LM06856).

PII: S0002-9343(04)00477-2

doi: 10.1016/j.amjmed.2004.06.023

The American Journal of Medicine
Volume 117, Issue 9 , Pages 643-649 , 1 November 2004

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