The American Journal of Medicine
Volume 110, Issue 7 , Pages 558-562, May 2001

Management of small renal tumors: an overview

  • Donal N Reddan, MB (MRCPI)

      Affiliations

    • Division of Nephrology (DNR), Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    • Corresponding Author InformationRequests for reprints should be addressed to Donal Reddan, MB, MRCPI, Duke University Medical Center, Department of Medicine, Division of Nephrology, Box 3014, Durham, North Carolina 27705
  • ,
  • Ganesh V Raj, MD, PhD

      Affiliations

    • Division of Urology (GVR, TJP), Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
  • ,
  • Thomas J Polascik, MD

      Affiliations

    • Division of Urology (GVR, TJP), Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA

Received 28 August 2000; received in revised form 5 January 2001; accepted 5 January 2001.

Abstract 

The incidental finding of a small renal mass poses a therapeutic dilemma. The traditional treatment of clinically important masses has been radical nephrectomy. Recently, nephron-sparing surgery has emerged as a viable alternative; and experimental minimally invasive percutaneous tissue ablation techniques, including cryotherapy and radiofrequency ablation, are being evaluated. In this review, we discuss the dilemma posed by frequent renal imaging and the increased proportion of incidental tumors being detected, the limitations of needle biopsies for histologic diagnosis, nephron-conserving and minimally invasive surgery, and the possible merits of radiofrequency ablation and cryotherapy. We envision a defined role for minimally invasive percutaneous or extracorporeal ablation of small renal tumors.

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 Dr. Reddan is supported by a National Kidney Foundation Research Fellowship Grant.

PII: S0002-9343(01)00650-7

The American Journal of Medicine
Volume 110, Issue 7 , Pages 558-562, May 2001