The American Journal of Medicine
Volume 110, Issue 5 , Pages 361-369 , 1 April 2001

Prognostic value of pharmacologic stress echocardiography in patients with left bundle branch block1

  • Lauro Cortigiani, MD

      Affiliations

    • Cardiovascular Unit (LC), Lucca Hospital, Lucca, Italy
    • Corresponding Author InformationRequests for reprints should be addressed to Lauro Cortigiani, MD, Unità Operativa di Malattie Cardiovascolari, Ospedale Campo di Marte, 55032 Lucca, Italy
    • ,
  • Eugenio Picano, MD, PhD

      Affiliations

    • Institute of Clinical Physiology (EP), CNR, Pisa, Italy
    • ,
  • Carlo Vigna, MD

      Affiliations

    • IRCCS, CSS Hospital (CV), S. Giovanni Rotondo, Italy
    • ,
  • Fabio Lattanzi, MD

      Affiliations

    • Cardiovascular Unit (FL), Pontedera Hospital, Pontedera, Italy
    • ,
  • Claudio Coletta, MD

      Affiliations

    • Cardiovascular Unit (CC), “S. Spirito” Hospital, Roma, Italy
    • ,
  • Egidio Mariotti, MD

      Affiliations

    • Cardiovascular Unit (EM), Pesaro Hospital, Pesaro, Italy
    • ,
  • Riccardo Bigi, MD

      Affiliations

    • Cardiovascular Research Foundation (RB), Castelfranco Veneto Hospital, Castelfranco Veneto, Italy
    • ,
  • on behalf of the EPIC (Echo Persantine International Cooperative) and EDIC (Echo Dobutamine International Cooperative) Study Groups

Received 7 September 2000 ,Revised 19 December 2000 ,Accepted 19 December 2000.

References 

  1. Rotman M, Triebwasser . A clinical and follow-up study of right and left bundle branch block. Circulation. 1975;51:477–485
  2. Schneider JF, Thomas HS, Kreger BE, et al.  Newly acquired left bundle branch block (the Framingham study). Ann Intern Med. 1979;90:303–310
  3. Fahy GJ, Pinski SL, Miller DP, et al.  Natural history of isolated left bundle branch block. Am J Cardiol. 1996;77:1185–1190
  4. Haft JI, Herman MV, Gorlin R. Left bundle branch block. Etiologic, hemodynamic, and ventriculographic considerations. Circulation. 1971;43:279–283
  5. Schneider JF, Thomas HS, Sorlie P, et al.  Comparative features of newly acquired left and right bundle branch block in the general population (the Framingham study). Am J Cardiol. 1981;47:931–940
  6. Lewis CM, Dagenais GR, Friesinger GC, Ross RS. Coronary arteriographic appearances in patients with left bundle branch block. Circulation. 1970;41:299–307
  7. Whinnery JE, Froehlicher VF, Stewart AJ, et al.  The electrocardiographic response to maximal treadmill exercise of asymptomatic men with left bundle branch block. Am Heart J. 1977;94:316–324
  8. Orzan F, Garcia E, Mathur VS, Hall RJ. Is the treadmill exercise test useful for evaluating coronary artery disease in patients with complete left bundle-branch block?. Am J Cardiol. 1978;42:36–40
  9. Hirzel HO, Senn M, Nuesch K, et al.  Thallium-201 scintigraphy in complete left bundle branch block. Am J Cardiol. 1984;53:764–769
  10. DePuey EG, Guertler-Krawczynska E, Robbins WL. Thallium-201 SPECT in coronary artery disease patients with left bundle branch block. J Nucl Med. 1988;29:1479–1485
  11. Ebersole DG, Heironimus J, Toney MO, Billingsley J. Comparison of exercise and adenosine technetium-99m sestamibi scintigraphy for diagnosis of coronary artery disease in patients with left bundle branch block. Am J Cardiol. 1993;71:450–453
  12. Jukema JW, van der Wall EE, van der Vis-Melsen MJ, Kruyswijk HH, Bruschke AV. Dipyridamole thallium-201 scintigraphy for improved detection of left anterior coronary artery stenosis in patients with left bundle branch block. Eur Heart J. 1993;14:53–56
  13. O’Keefe JH, Bateman TM, Barnhart CS. Adenosine thallium-201 is superior to exercise thallium-201 for detecting coronary artery disease in patients with left bundle branch block. J Am Coll Cardiol. 1993;21:1332–1338
  14. Vaduganathan P, He Z-X, Raghavan C, Mahmarian JJ, Verani MS. Detection of left anterior descending coronary artery stenosis in patients with left bundle branch block (exercise, adenosine or dobutamine imaging?). J Am Coll Cardiol. 1996;28:543–550
  15. Gil V, Almeida M, Ventosa M, et al.  Prognosis in patients with left bundle branch block and normal thallium-201 scintigraphy. J Nucl Cardiol. 1998;5:414–417
  16. Nallamothu N, Bagheri B, Acio ER, Heo J, Iskandrian AE. Prognostic value of stress myocardial perfusion single photon emission computed tomography imaging in patients with left bundle branch block. J Nucl Cardiol. 1997;4:487–493
  17. Nigam A. Humen DP. Prognostic value of myocardial perfusion imaging with exercise and/or dipyridamole hyperemia in patients with preexisting left bundle branch block. J Nucl Med. 1998;39:579–581
  18. Wagdy HM, Hodge D, Christian TF, Miller TD, Gibbons RJ. Prognostic value of vasodilator myocardial imaging in patients with left bundle branch block. Circulation. 1998:1563–1570.
  19. Cheitlin MD, Alpert JS, Armstrong WF, et al.  ACC/AHA guidelines for the clinical application of echocardiography (executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Clinical Application of Echocardiography)). J Am Coll Cardiol. 1997;29:862–879
  20. Geleijnse ML, Vigna G, Kasprzak JD, et al.  Usefulness and limitations of dobutamine-atropine stress echocardiography for the diagnosis of coronary artery disease in patients with left bundle branch block. Eur Heart J. 2000;21:1666–1673
  21. Mairesse GH, Marwick TH, Arnese M, et al.  Improved identification of coronary artery disease in patients with left bundle branch block by the use of dobutamine stress echocardiography and comparison with myocardial perfusion tomography. Am J Cardiol. 1995;76:321–325
  22. Diamond GA, Forrester JS. Analysis of probability as an aid in the clinical diagnosis of coronary artery disease. N Engl J Med. 1979;300:1350–1358
  23. Picano E, Lattanzi F, Masini M, Distante A, L’Abbate A. High dose dipyridamole echocardiography test in effort angina pectoris. J Am Coll Cardiol. 1986;8:846–854
  24. Picano E, Mathias W, Pingitore A, Bigi R, Previtali M. Safety and tolerability of dobutamine-atropine stress echocardiography (a prospective, multicentre study). Lancet. 1994;344:1190–1192
  25. Picano E, Pingitore A, Conti U, et al.  Enhanced sensitivity for detection of coronary artery disease by addition of atropine to dipyridamole echocardiography. Eur Heart J. 1993;14:1216–1222
  26. Schiller NB, Shah PM, Crawford M, et al.  Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989;2:358–367
  27. McDonald IG. Echocardiographic demonstration of abnormal motion of the intraventricular septum in left bundle branch block. Circulation. 1973;48:272–280
  28. Abbasi AS, Eber LM, McAlpin RN, Kattus AA. Paradoxical motion of the intraventricular septum in left bundle branch block. Circulation. 1974;49:423–427
  29. Dillon JC, Chang S, Feigenbaum H. Echocardiographic manifestations of left bundle branch block. Circulation. 1974;49:876–880
  30. Fujii J, Watanabe H, Watanabe T, et al.  M-mode, and cross-sectional echocardiographic study of the left ventricular wall motions in complete bundle branch block. Br Heart J. 1979;42:255–260
  31. Strasberg B, Rich S, Lam W, et al.  M-mode echocardiography in left bundle branch block (significance of frontal plane QRS axis). Am Heart J. 1982;104:775–779
  32. Senior R, Lahiri A. Enhanced detection of myocardial ischemia by stress dobutamine echocardiography utilizing the “biphasic” response of wall thickening during low and high dose dobutamine infusion. J Am Coll Cardiol. 1995;26:26–32
  33. Arnese M, Fioretti P, Cornel J, et al.  Akinesis becoming dyskinesis during high dose dobutamine stress echocardiography (a marker of ischemia or a purely mechanical phenomenon?). Am J Cardiol. 1994;73:896–899
  34. Picano E, Landi P, Bolognese L, et al.  Prognostic value of dipyridamole echocardiography early after uncomplicated myocardial infarction (a large-scale, multicenter trial). Am J Med. 1993;95:608–618
  35. Sgarbossa EB, Pinski SL, Barbagelata A, et al.  Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle branch block. N Engl J Med. 1996;334:481–487
  36. Ono S, Nohara R, Kambara H, Okuda K, Kawai C. Regional myocardial perfusion and glucose metabolism in experimental left bundle branch block. Circulation. 1992;85:1125–1131
  37. Cortigiani L, Picano E, Landi P, et al.  Value of pharmacologic stress echocardiography in risk stratification of patients with single-vessel disease (a report from the Echo-Persantine and Echo-Dobutamine International Cooperative Studies). J Am Coll Cardiol. 1998;32:69–74
  38. Picano E. Pathogenetic mechanisms of stress. In: Picano E, ed. Stress Echocardiography, 3rd edition. Heidelberg: Springer-Verlag, 1997:62–75.
  39. Picano E, Bedetti G, Varga A, Cseh E. The comparable diagnostic accuracy of dobutamine and dipyridamole stress echocardiography (a meta-analysis). Coron Artery Dis. 2000;11:151–159
  40. Schroeder K, Wieckhorst A, Voller H. Comparison of the prognostic value of dipyridamole and dobutamine stress echocardiography in patients with known or suspected coronary artery disease. Am J Cardiol. 1997;79:1516–1517
  41. Minardi G, Di Segni M, Manzara CC, et al.  Diagnostic and prognostic value of dipyridamole and dobutamine stress echocardiography in patients with acute myocardial infarction. Am J Cardiol. 1997;80:847–851
  42. Pingitore A, Picano E, Varga A, et al.  Prognostic value of pharmacological stress echocardiography in patients with known or suspected coronary artery disease (a prospective, large-scale, multicenter, head-to-head comparison between dipyridamole and dobutamine test. Echo-Persantine International Cooperative (EPIC) and Echo-Dobutamine International Cooperative (EDIC) Study Groups). J Am Coll Cardiol. 1999;34:1769–1777
  43. Hoffmann R, Lethen H, Marwick T, et al.  Analysis of interinstitutional observer agreement in interpretation of dobutamine stress echocardiograms. J Am Coll Cardiol. 1996;27:330–336
  44. Varga A, Picano E, Dodi C, et al.  Madness and method in stress echo reading. Eur Heart J. 1999;20:1271–1275
  45. Severi S, Picano E, Michelassi C, et al.  Diagnostic and prognostic value of dipyridamole echocardiography in patients with suspected coronary artery disease. Comparison with exercise electrocardiography. Circulation. 1994;89:1160–1173
  46. Cortigiani L, Paolini EA, Nannini E. Dipyridamole stress echocardiography for risk stratification in hypertensive patients with chest pain. Circulation. 1998;98:2855–2859
  47. Iskander S, Iskandrian AE. Risk assessment using single-photon emission computed tomographic technetium-99m sestamibi imaging. J Am Coll Cardiol. 1998;32:57–62

PII: S0002-9343(01)00630-1

The American Journal of Medicine
Volume 110, Issue 5 , Pages 361-369 , 1 April 2001

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