Osteoporosis commonly afflicts patients with inflammatory bowel disease, and many factors link the 2 states together. A literature review was conducted about the pathophysiology of osteoporosis in relation to inflammatory bowel disease. Screening guidelines for osteoporosis in general as well as those directed at patients with inflammatory bowel disease are reviewed, as are currently available treatment options. The purpose of this article is to increase physician awareness about osteopenia and osteoporosis occurring in patients with inflammatory bowel disease and to provide basic, clinically relevant information about the pathophysiology and guidelines to help them treat these patients in a cost-effective manner.
aDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City
bSection of Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma City
cSection of Rheumatology, Immunology and Allergy, University of Oklahoma Health Sciences Center, Oklahoma City
Requests for reprints should be addressed to Mary Beth Humphrey, MD, PhD, Department of Medicine, University of Oklahoma Health Sciences Center, 975 N.E. 10th St., BRC 209, Oklahoma City, OK 73104
Funding: Dr. Humphrey received funding from US Department of Veterans Affairs.
Conflict of Interest: None.
Authorship: All authors contributed to writing this manuscript.
ABSTRACT
