The American Journal of Medicine
Volume 81, Issue 6 , Pages 969-973 , December 1986

Characterization of a distinct subgroup of high-risk persons with Kaposi's sarcoma and good prognosis who present with normal T4 cell number and T4:T8 ratio and negative HTLV-III/LAV serologic test results

Received 6 December 1985 ,Accepted 7 January 1986.

References 

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  2. Mitsuyasu RT, Groopman JE. Biology and therapy of Kaposi's sarcoma. Semin Oncol. 1984;11:53–54
  3. Ziegler J, Templeton AC, Vogel CL. Kaposi's sarcoma: a comparison of classical endemic and epidemic forms. Semin Oncol. 1984;11:47–52
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  5. Taylor J, Afrasiabi R, Fahey JL, et al.  A prognostically significant classification of immune changes in AIDS with Kaposi's sarcoma. Blood. 1986;67:666–671
  6. Fahey JL, Prince H, Weaver M, et al.  Quantitative changes in T helper or T suppressor/cytotoxic lymphocytes subsets that distinguish acquired immune-deficiency syndrome from other immune subset disorders. Am J Med. 1984;76:95–100
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  8. Martinez-Maza O, Britton S. Frequencies of the separate human B cell subsets activatable to Ig secretion by Epstein-Barr virus and pokeweed mitogen. J Exp Med. 1983;157:1808–1814
  9. Salahuddin SZ, Groopman DE, Markham PD, et al.  HTLV-III in symptom free seronegative persons. Lancet. 1984;II:1418–1420
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  11. Salazar-Gonzales JF, Moody DJ, Giorgi JV, Martinez-Maza O, Mitsuyasu RT, Fahey JL. Reduced ecto-5′-nucleotidase activity and enhanced OKT10 and HLA-DR expression on CD8 (T-suppressor/cytotoxic) lymphocytes in the acquired immune deficiency syndrome: evidence of CD8 cell immaturity. J Immunol. 1985;135:1778–1785
  12. CDC . Revision of the case definition of acquired immune deficiency syndrome for national reporting. Morbid Mortal Weekly Rep. 1985;34:373–375
  13. Maring C, Fiorini G, Boneschi V, et al.  Immunologic and immunogenetic features of primary Kaposi's sarcoma. Cancer. 1985;55:1899–1901
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  15. Biggar RJ, Melbye M, Kestems L, et al.  Kaposi's sarcoma in Zaire is not associated with HTLV-III infection. N Engl J Med. 1984;311:1051–1052

 This work was supported by Grants CA-12800, AI-20672, AI-15332, and K08-CA-00932 from the National Institutes of Health, a fellowship from the American Cancer Society (Dr. Mitsuyasu), and a grant from the Concern Foundation of Los Angeles.

PII: 0002-9343(86)90389-X

The American Journal of Medicine
Volume 81, Issue 6 , Pages 969-973 , December 1986