The American Journal of Medicine
Volume 76, Issue 6 , Pages 1021-1026 , June 1984

Parathyroid glands in familial benign hypercalcemia (familial hypocalciuric hypercalcemia)

  • William M. Law Jr., M.D.

      Affiliations

    • From the Endocrine Research Unit, Division of Endocrinology and Metabolism, Department of Medicine, and the Department of Pathology, Mayo Clinic, Rochester, Minnesota.
    • Current address: University of Tennessee, Physicians' Office Building, Suite 303, 1928 Alcoa Highway, Knoxville, Tennessee 37920.
    • ,
  • J.Aidan Carney, M.D.

      Affiliations

    • From the Endocrine Research Unit, Division of Endocrinology and Metabolism, Department of Medicine, and the Department of Pathology, Mayo Clinic, Rochester, Minnesota.
    • ,
  • Hunter Heath III, M.D.

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Dr. Hunter Heath III, Mayo Clinic, 5-164 West Joseph Building, Rochester, Minnesota 55905.
    • From the Endocrine Research Unit, Division of Endocrinology and Metabolism, Department of Medicine, and the Department of Pathology, Mayo Clinic, Rochester, Minnesota.

,Accepted 4 January 1984.

References 

  1. Foley TP, Harrison HC, Arnaud CD, Harrison HE. Familial benign hypercalcemia. J Pediatr. 1972;81:1060–1067
  2. Paterson CR, Gunn A. Familial benign hypercalcemia. Lancet. 1981;II:61–63
  3. Heath H, Purnell DC. Urinary cyclic 3′,5′-adenosine monophosphate responses to exogenous and endogenous parathyroid hormone in familial benign hypercalcemia and primary hyperparathyroidism. J Lab Clin Med. 1980;96:974–984
  4. Menko FH, Bijvoet OLM, Fronen JLHH, et al. Familial benign hypercalcemia. Study of a large family. Q J Med. 1983;52:120–140
  5. Marx SJ, Attie MF, Levine MA, Spiegel AM, Downs RW, Lasker RD. The hypocalciuric or benign variant of familial hypercalcemia: clinical and biochemical features in fifteen kindreds. Medicine (Baltimore). 1981;60:397–412
  6. Marx SJ, Spiegel AM, Levine MA, et al. Familial hypocalciuric hypercalcemia. The relation to primary parathyroid hyperplasia. N Engl J Med. 1982;307:416–426
  7. Attie MF, Gill JR, Stock JL, et al. Urinary calcium excretion in familial hypocalciuric hypercalcemia. Persistence of relative hypocalciuria after induction of hypoparathyroidism. J Clin Invest. 1983;72:667–676
  8. Marx SJ, Stock JL, Attie MF, et al. Familial hypocalciuric hypercalcemia: recognition among patients referred after unsuccessful parathyroid exploration. Ann Intern Med. 1980;92:351–356
  9. Alexandre C, Riffat G, Chappard D, Chappard C, Fulchiron H. Une cause rare d'hypercalcémie: l'hypercalcémie hypocalciurique familiale. Nouv Presse Med. 1982;11:2399–2403
  10. Baxi SC, Vanderlaan WP. Familial hypocalciuric hypercalcemia. West J Med. 1982;136:149–151
  11. Davies M, Klimiuk PS, Adams PH, Lumb GA, Large DM, Anderson DC. Familial hypocalciuric hypercalcemia and acute pancreatitis. Br Med J. 1981;282:1023–1025
  12. Doumith R, Ulmann A, Biclet P, Rieu M, Dubost CL. Syndrome d'hypercalcémie-hypocalciurie: une cause meconnue d'hypercalcémie. Nouv Presse Med. 1980;9:1157–1159
  13. Fujita T, Watanabe N, Fukase M, et al. Familial hypocalciuric hypercalcemia involving four members of a kindred including a girl with severe neonatal primary hyperparathyroidism. Min Electrolyte Metab. 1983;9:51–54
  14. Sereni D, Chevalier P, Cremer GA, Boissonnas A, Dubost C, Laroche C. L'hypercalcémie hypocalciurique familiale. A propos de deux observations. Ann Med Interne (Paris). 1982;133:281–284
  15. Sharp CF, Rude RK, Oldham SB, Singer FR. Familial benign hypercalcemia (abstr). Clin Res. 1978;26:428A
  16. Thorgeirsson U, Costa J, Marx SJ. The parathyroid glands in familial hypocalciuric hypercalcemia. Hum Pathol. 1981;12:229–237
  17. Toss G, Arnqvist H, Eneström S, Karlberg B, Larsson L, Lennqvist S. Familial hypocalciuric hypercalcemia (abstr). Min Electrolyte Metab. 1981;6:268
  18. Heath H, Lambert PW, Service FJ, Arnaud SB. Calcium homeostasis in diabetes mellitus. J Clin Endocrinol Metab. 1979;49:462–466
  19. Schantz A. The microscopical pathology of primary hyperparathyroidism. Ann Clin Lab Sci. 1979;9:314–318
  20. Wang C-A. The anatomic basis of parathyroid surgery. Ann Surg. 1976;183:271–275
  21. Dekker A, Dunsford HA, Geyer SJ. The normal parathyroid gland at autopsy: the significance of stromal fat in adult patients. J Pathol. 1979;128:127–132
  22. Akerström G, Grimelius L, Johansson H, Lundqvist H, Pertoft H, Bergstrom R. The parenchymal cell mass in normal human parathyroid glands. Acta Pathol Microbiol Scand. 1981;89:367–375
  23. Dufour DR, Wilkerson SY. Factors related to parathyroid weight in normal persons. Arch Pathol Lab Med. 1983;107:167–172
  24. Brown EM, Brennan MF, Hurwitz S, et al. Dispersed cells prepared from human parathyroid glands: distinct calcium sensitivity of adenomas versus primary hyperplasia. J Clin Endocrinol Metab. 1978;46:267–275
  25. Marx SJ, Spiegel AM, Sharp ME, et al. Adenosine 3′,5′monophosphate response to parathyroid hormone: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. J Clin Endocrinol Metab. 1980;50:546–549

☆ This work was supported in part by grants from the National Institutes of Health (AM-19607) and the Mayo Foundation. Dr. Law was a Research Fellow of the Mayo Foundation and Mayo Graduate School of Medicine.

PII: 0002-9343(84)90852-0

The American Journal of Medicine
Volume 76, Issue 6 , Pages 1021-1026 , June 1984

Article Tools