The American Journal of Medicine
Volume 77, Issue 3 , Pages 533-536, September 1984

New lessons favoring physicians' support of clinical trials

  • Stephen T. Miller, M.D.

      Affiliations

    • Corresponding Author InformationRequests for reprints should be addressed to Dr. Stephen T. Miller, University of Tennessee, 800 Madison Avenue, Memphis, Tennessee 38163.
    • From the Departments of Medicine and Community Medicine and the Program on Human Values and Ethics, University of Tennessee Center for the Health Sciences, Memphis, Tennessee.
    • ,
  • Clifton Perry, Ph.D.

      Affiliations

    • From the Departments of Medicine and Community Medicine and the Program on Human Values and Ethics, University of Tennessee Center for the Health Sciences, Memphis, Tennessee.

Memphis, Tennessee USA

Accepted 7 March 1984.

Abstract 

The publications of the Hypertension Detection and Follow-up Program and the Multiple Risk Factor Intervention Trial have produced different opinions concerning the therapeutic implications of their results. However, they provide new lessons concerning the design of clinical trials and the ethical implications of this research. Their experiences clearly illustrate the scientific requirements for controlled clinical trials and clarify the ethical validity of future investigations for medical researchers and the medical profession.

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PII: 0002-9343(84)90115-3

The American Journal of Medicine
Volume 77, Issue 3 , Pages 533-536, September 1984

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