The American Journal of Medicine
Volume 28, Issue 5 , Pages 824-831 , May 1960

A simplified closed circuit helium dilution method for the determination of the residual volume of the lungs

  • George R. Meneely, M.D.

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
  • ,
  • Con O.T. Ball

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
  • ,
  • Ross C. Kory, M.D.

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
    • Present address: Veterans Administration Center, Wood, Wisconsin.
  • ,
  • James J. Callaway, M.D.

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
  • ,
  • Joseph M. Merrill, M.D.

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
  • ,
  • R.E. Mabe, M.D.

      Affiliations

    • Present address: Veterans Administration Center, Wood, Wisconsin.
    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
  • ,
  • Dan C. Roehm, M.D.

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.
  • ,
  • Nolan L. Kaltreider, M.D.

      Affiliations

    • From the Department of Medicine, Vanderbilt University School of Medicine and The Research Laboratory, Thayer Veterans Administration Hospital, Nashville, Tennessee, and The Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York.

References 

  1. Meneely GR, Kaltreider NL. Use of helium for determination of pulmonary capacity. In: Proc. Soc. Exper. Biol. & Med. 46:1941;p. 266
  2. McMichael J. A rapid method of determining lung capacity. Clin. Sc. 1939;4:167
  3. Meneely GR, Kaltreider NL. The volume of the lung determined by helium dilution. Description of the method and comparison with other procedures. J. Clin. Invest. 1949;28:129
  4. Gilson JC, Hugh-Jones P. The measurement of the total lung volume and breathing capacity. Clin. Sc. 1949;7:185
  5. Fowler WS. Specific tests of pulmonary function. A. Lung volumes. In:  Comroe JH editors. Methods in Medical Research. vol. 2:Chicago: The Year Book Publishers; 1950;p. 181
  6. Herrald FJC, McMichael J. Determination of lung volume: Simple constant volume modification of Christie's method. In: Proc. Roy. Soc. London, s. B. 126:1939;p. 491
  7. Lassen HCA, Cournand A, Richards DW. Distribution of respiratory gases in closed breathing circuit. I. In normal subjects. J. Clin. Invest. 1937;16:1
  8. Cournand A, Lassen HCA, Richards DW. Distribution of respiratory gases in closed breathing circuit. II. Pulmonary fibrosis and emphysema. J. Clin. Invest. 1937;16:9
  9. Christie RV. The lung volume and its subdivisions. J. Clin. Invest. 1932;11:1099

 This investigation was supported in part through grants-in-aid for research from the Commonwealth Fund and the American College of Chest Physicians.

PII: 0002-9343(60)90137-6

The American Journal of Medicine
Volume 28, Issue 5 , Pages 824-831 , May 1960